C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxysteroid (11-beta) dehydrogenase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176387 HSD11B2 9606 + 16:67430652-67437553 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326152 HSD11B2-001 67431117-67437553 protein_coding
  ENST00000566606 HSD11B2-003 67431366-67436134 nonsense_mediated_decay
  ENST00000567684 HSD11B2-002 67430652-67436261 processed_transcript
  ENST00000569303 HSD11B2-004 67431122-67433184 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000326152ENST00000566606ENST00000567684ENST00000569303
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000326152 2.322±0.00 N/A 1.282±0.35 10.441±1.21 0.048±0.00 132.690±132.64 0.162±0.00 N/A N/A 4.435±1.53 14.049±9.70 1.531±0.68
ENST00000566606 N/A 0.094±0.00 N/A N/A N/A N/A N/A N/A N/A 4.199±0.00 N/A 1.428±0.00
ENST00000567684 N/A N/A N/A N/A N/A N/A N/A N/A 1.358±0.00 N/A 3.269±0.00 N/A
ENST00000569303 N/A N/A N/A N/A 0.108±0.00 N/A N/A 0.462±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005JW CIL_0005JW_0001 CGP 16:67394419-67437553
CIL_0005JT CIL_0005JT_0001 CGP 16:67430652-67481237

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0002017 IEA regulation of blood volume by renal aldosterone
GO:0003845 IEA 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
GO:0005496 IEA steroid binding
GO:0005737 IEA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0007565 IEA female pregnancy
GO:0008152 IEA metabolic process
GO:0008211 IEA glucocorticoid metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0032094 IEA response to food
GO:0032868 IEA response to insulin
GO:0042493 IEA response to drug
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0048545 IEA response to steroid hormone
GO:0051287 IEA NAD binding
GO:0051384 IEA response to glucocorticoid
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001975 hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 protein_coding Danio_rerio
ENSMUSG00000031891 Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 protein_coding Mus_musculus

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