C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled class receptor 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177283 FZD8 9606 - 10:35638249-35642278 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374694 FZD8-001 35638249-35642278 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374694
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374694 2.193±0.00 5.057±0.00 0.567±0.00 1.083±0.08 2.531±1.19 2.424±1.89 0.936±0.69 3.897±3.60 0.719±0.08 1.120±0.12 1.069±0.38 2.477±0.91 1.188±0.36 1.925±0.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Q5 CIL_0008Q5_0001 VISTA 10:35336454-35938314
CIL_0008CR CIL_0008CR_0001 VISTA 10:35383964-35987004
CIL_0008Q1 CIL_0008Q1_0001 VISTA 10:35483344-36085363
CIL_0006FP CIL_0006FP_0002 CGP 10:35605410-35642278

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001525 IEA angiogenesis
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001944 IBA vasculature development
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005102 IEA receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IBA plasma membrane
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008406 IBA gonad development
GO:0016020 IEA membrane
GO:0016021 TAS integral component of membrane
GO:0016055 IEA Wnt signaling pathway
GO:0017147 IBA Wnt-protein binding
GO:0030165 IPI PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033077 IBA T cell differentiation in thymus
GO:0042813 IBA Wnt-activated receptor activity
GO:0042995 IBA cell projection
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0060070 IBA canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038569 fzd8b frizzled homolog 8b protein_coding Danio_rerio
ENSDARG00000045444 fzd8a frizzled homolog 8a protein_coding Danio_rerio
ENSMUSG00000036904 Fzd8 frizzled homolog 8 (Drosophila) protein_coding Mus_musculus

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