C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TGFB-induced factor homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177426 TGIF1 9606 + 18:3411608-3459978 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330513 TGIF1-003 3451677-3458411 protein_coding
  ENST00000343820 TGIF1-002 3449704-3458411 protein_coding
  ENST00000345133 TGIF1-016 3451670-3458123 protein_coding
  ENST00000400167 TGIF1-201 3453774-3458406 protein_coding
  ENST00000401449 TGIF1-202 3411927-3458406 protein_coding
  ENST00000405385 TGIF1-203 3449651-3458406 protein_coding
  ENST00000407501 TGIF1-006 3449882-3458349 protein_coding
  ENST00000472042 TGIF1-004 3455414-3458411 protein_coding
  ENST00000546979 TGIF1-005 3450036-3457475 protein_coding
  ENST00000547233 TGIF1-009 3412204-3418846 retained_intron
  ENST00000548489 TGIF1-204 3412856-3458406 protein_coding
  ENST00000549253 TGIF1-012 3449413-3457456 protein_coding
  ENST00000549468 TGIF1-018 3453774-3457580 protein_coding
  ENST00000549546 TGIF1-017 3451724-3457918 protein_coding
  ENST00000549780 TGIF1-011 3448499-3457839 protein_coding
  ENST00000550958 TGIF1-010 3412854-3457574 protein_coding
  ENST00000551333 TGIF1-019 3455152-3457594 protein_coding
  ENST00000551402 TGIF1-007 3450177-3457113 protein_coding
  ENST00000551541 TGIF1-015 3451593-3457944 protein_coding
  ENST00000551557 TGIF1-013 3449537-3450040 processed_transcript
  ENST00000552383 TGIF1-008 3411608-3457684 protein_coding
  ENST00000577543 TGIF1-020 3450212-3457604 protein_coding
  ENST00000618001 TGIF1-001 3447609-3459978 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330513ENST00000343820ENST00000345133ENST00000400167ENST00000401449ENST00000405385ENST00000407501ENST00000472042ENST00000546979ENST00000549546ENST00000549780ENST00000551541ENST00000577543
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330513 N/A N/A N/A 0.360±0.00 N/A N/A 0.097±0.00 N/A N/A N/A N/A 3.474±0.00 N/A 2.858±0.00
ENST00000343820 4.801±0.00 N/A 1.211±0.00 0.746±0.00 3.785±0.00 12.591±0.00 N/A 3.230±0.00 1.275±0.53 10.419±0.00 3.567±0.00 8.379±0.51 8.696±1.75 4.802±0.00
ENST00000345133 N/A N/A N/A 0.625±0.00 N/A N/A N/A N/A 1.751±0.00 N/A N/A N/A N/A N/A
ENST00000400167 N/A N/A N/A N/A N/A N/A N/A 0.191±0.00 N/A N/A 0.326±0.00 13.175±0.00 9.243±0.53 7.887±0.00
ENST00000401449 N/A N/A N/A N/A N/A 1.794±0.00 N/A N/A N/A N/A N/A 3.058±0.00 N/A N/A
ENST00000405385 N/A N/A N/A N/A N/A 1.676±0.00 0.097±0.00 3.130±0.00 N/A N/A 2.707±0.00 N/A N/A N/A
ENST00000407501 8.878±0.00 1.745±0.00 N/A 0.347±0.00 6.508±0.00 10.502±0.00 4.016±0.00 9.158±0.00 3.087±0.00 17.907±0.00 4.904±0.00 15.018±2.40 11.583±4.82 5.412±1.06
ENST00000472042 N/A 0.923±0.00 N/A 0.133±0.00 N/A 2.013±0.00 0.135±0.00 N/A N/A 2.165±0.00 N/A 3.727±0.76 N/A 1.298±0.00
ENST00000546979 N/A N/A N/A N/A 4.739±0.00 N/A N/A N/A N/A 2.900±0.00 N/A N/A N/A N/A
ENST00000549546 N/A N/A 2.130±0.00 1.198±0.08 6.260±0.00 N/A N/A N/A 4.746±0.00 3.536±0.00 3.706±2.67 10.314±1.71 12.123±1.25 5.395±0.00
ENST00000549780 N/A N/A N/A N/A N/A N/A N/A 0.796±0.00 N/A N/A N/A N/A N/A N/A
ENST00000551541 N/A N/A N/A N/A N/A N/A 0.098±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000577543 N/A 5.511±0.00 N/A N/A N/A N/A N/A 1.005±0.00 N/A N/A N/A 6.420±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001843 IEA neural tube closure
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0007368 IEA determination of left/right symmetry
GO:0008285 IEA negative regulation of cell proliferation
GO:0009953 IEA dorsal/ventral pattern formation
GO:0010467 TAS gene expression
GO:0010470 IEA regulation of gastrulation
GO:0010629 IEA negative regulation of gene expression
GO:0038092 IEA nodal signaling pathway
GO:0042493 IEA response to drug
GO:0045666 IEA positive regulation of neuron differentiation
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048387 IEA negative regulation of retinoic acid receptor signaling pathway
GO:0060041 IEA retina development in camera-type eye
GO:0070410 IEA co-SMAD binding
GO:0071363 IEA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059337 tgif1 transforming growth factor-beta-induced factor 1 protein_coding Danio_rerio
ENSMUSG00000047407 Tgif1 TGFB-induced factor homeobox 1 protein_coding Mus_musculus

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