C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: jun proto-oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177606 JUN 9606 - 1:58780788-58784327 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371222 JUN-001 58780788-58784327 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371222
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371222 118.747±0.00 62.984±0.00 13.580±0.00 18.934±11.91 69.932±46.12 44.641±30.23 14.834±4.85 16.760±14.78 15.284±10.05 75.834±44.64 30.330±2.93 127.890±140.80 75.248±15.18 37.210±10.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001N6 CIL_0001N6_0001 CGP 1:58654739-58784327
CIL_0008Y5 CIL_0008Y5_0001 VISTA 1:58756653-59358420
CIL_0007ZB CIL_0007ZB_0001 VISTA 1:58756772-59358111
CIL_0001N7 CIL_0001N7_0001 CGP 1:58780788-59767675

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000228 TAS nuclear chromosome
GO:0000790 IEA nuclear chromatin
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IC sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001190 IC RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IEA angiogenesis
GO:0001774 IEA microglial cell activation
GO:0001836 IEA release of cytochrome c from mitochondria
GO:0001889 IEA liver development
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003151 IEA outflow tract morphogenesis
GO:0003677 TAS:IEA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IC RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0005100 IDA Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005719 IDA nuclear euchromatin
GO:0005829 IEA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007184 IDA SMAD protein import into nucleus
GO:0007568 IEA aging
GO:0007612 IEA learning
GO:0007623 IEA circadian rhythm
GO:0008134 IPI transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0009314 IEA response to radiation
GO:0009612 IEA response to mechanical stimulus
GO:0009987 IEA cellular process
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0017053 IEA transcriptional repressor complex
GO:0019899 IPI enzyme binding
GO:0030224 IEA monocyte differentiation
GO:0031103 IEA axon regeneration
GO:0031953 IEA negative regulation of protein autophosphorylation
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0032496 IEA response to lipopolysaccharide
GO:0034097 IEA response to cytokine
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035026 IEA leading edge cell differentiation
GO:0035497 IDA cAMP response element binding
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043392 IDA negative regulation of DNA binding
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0043922 IDA negative regulation by host of viral transcription
GO:0043923 IDA positive regulation by host of viral transcription
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045657 IEA positive regulation of monocyte differentiation
GO:0045740 IEA positive regulation of DNA replication
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IC positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051365 IEA cellular response to potassium ion starvation
GO:0051403 TAS stress-activated MAPK cascade
GO:0051591 IEA response to cAMP
GO:0051726 IEA regulation of cell cycle
GO:0051899 IEA membrane depolarization
GO:0060395 IDA SMAD protein signal transduction
GO:0070412 IPI R-SMAD binding
GO:0071277 IEA cellular response to calcium ion
GO:0071837 IEA HMG box domain binding
GO:1990441 IMP negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043531 jun jun proto-oncogene protein_coding Danio_rerio
ENSMUSG00000052684 Jun jun proto-oncogene protein_coding Mus_musculus

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