C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177700 POLR2L 9606 - 11:837356-842545 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322028 POLR2L-001 839721-842545 protein_coding
  ENST00000534030 POLR2L-002 837356-842529 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322028ENST00000534030
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322028 N/A 6.190±0.00 7.445±0.00 8.841±0.00 N/A 4.008±0.00 6.962±0.00 N/A N/A 24.210±0.00 6.856±0.00 N/A N/A
ENST00000534030 281.655±0.00 N/A 48.917±0.00 N/A 157.672±0.00 169.236±0.00 165.305±0.00 112.049±0.00 172.974±0.00 N/A 292.719±0.00 161.485±16.52 91.469±38.59

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ES CIL_0003ES_0001 CGP 11:826144-839831
CIL_0003ET CIL_0003ET_0001 CGP 11:832843-842545
CIL_0003EQ CIL_0003EQ_0001 CGP 11:837356-867116

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0001054 IBA RNA polymerase I activity
GO:0001055 IBA RNA polymerase II activity
GO:0001056 IBA RNA polymerase III activity
GO:0003677 IEA DNA binding
GO:0003899 TAS:IEA DNA-directed RNA polymerase activity
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005665 IDA DNA-directed RNA polymerase II, core complex
GO:0005666 IBA DNA-directed RNA polymerase III complex
GO:0005736 IBA DNA-directed RNA polymerase I complex
GO:0005829 TAS cytosol
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006351 IEA transcription, DNA-templated
GO:0006356 TAS regulation of transcription from RNA polymerase I promoter
GO:0006360 IBA transcription from RNA polymerase I promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0006383 TAS transcription from RNA polymerase III promoter
GO:0006385 TAS transcription elongation from RNA polymerase III promoter
GO:0006386 TAS termination of RNA polymerase III transcription
GO:0008270 IBA zinc ion binding
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0032481 TAS positive regulation of type I interferon production
GO:0045087 TAS innate immune response
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058349 polr2l polymerase (RNA) II (DNA directed) polypeptide L protein_coding Danio_rerio
ENSMUSG00000038489 Polr2l polymerase (RNA) II (DNA directed) polypeptide L protein_coding Mus_musculus

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