C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH2B adaptor protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178188 SH2B1 9606 + 16:28846600-28874212 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322610 SH2B1-001 28846689-28874205 protein_coding
  ENST00000337120 SH2B1-002 28862804-28874201 protein_coding
  ENST00000359285 SH2B1-003 28863805-28874205 protein_coding
  ENST00000395532 SH2B1-006 28863975-28873607 protein_coding
  ENST00000538342 SH2B1-005 28863806-28873823 protein_coding
  ENST00000545570 SH2B1-004 28863559-28873627 protein_coding
  ENST00000561629 SH2B1-011 28867154-28871914 protein_coding
  ENST00000563591 SH2B1-008 28846600-28866284 protein_coding
  ENST00000563674 SH2B1-013 28863878-28873755 processed_transcript
  ENST00000566176 SH2B1-010 28866635-28871955 protein_coding
  ENST00000566209 SH2B1-007 28863030-28866264 protein_coding
  ENST00000567536 SH2B1-009 28846643-28869289 protein_coding
  ENST00000568868 SH2B1-014 28872340-28872813 protein_coding
  ENST00000569471 SH2B1-012 28869094-28872390 retained_intron
  ENST00000569651 SH2B1-015 28872253-28873893 protein_coding
  ENST00000618521 SH2B1-201 28863757-28874212 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000337120ENST00000359285ENST00000395532ENST00000538342ENST00000563591ENST00000563674ENST00000618521
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000337120 N/A 1.381±0.00 N/A 1.128±0.50 0.739±0.00 2.156±0.00 N/A 0.211±0.00 0.438±0.01 0.523±0.00 0.318±0.00 1.640±0.93 0.879±0.00 3.338±1.78
ENST00000359285 3.292±0.00 7.683±0.00 0.437±0.00 9.086±0.00 8.014±0.00 12.640±0.00 5.619±0.00 10.770±0.00 1.993±0.00 10.553±0.00 8.583±0.00 21.101±1.63 3.103±1.66 9.046±4.06
ENST00000395532 N/A N/A 1.293±0.00 N/A 4.859±0.00 1.601±0.00 0.292±0.00 1.327±0.00 N/A 0.410±0.00 N/A 7.226±3.71 1.702±0.00 N/A
ENST00000538342 3.381±0.00 N/A N/A N/A 1.180±0.00 11.328±0.00 N/A N/A N/A N/A 4.999±0.00 13.988±0.00 2.944±0.32 11.517±0.00
ENST00000563591 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.037±0.00 N/A N/A N/A
ENST00000563674 N/A N/A 1.748±0.00 N/A N/A N/A N/A N/A N/A N/A 1.945±0.00 N/A N/A N/A
ENST00000618521 N/A N/A N/A 1.946±0.00 N/A N/A N/A N/A N/A N/A N/A 0.772±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006928 IEA cellular component movement
GO:0007596 TAS blood coagulation
GO:0016020 IEA membrane
GO:0030032 IEA lamellipodium assembly
GO:0035556 IEA intracellular signal transduction
GO:0045840 IEA positive regulation of mitosis
GO:2000278 IEA regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057679 sh2b1 SH2B adaptor protein 1 protein_coding Danio_rerio
ENSMUSG00000030733 Sh2b1 SH2B adaptor protein 1 protein_coding Mus_musculus

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