C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: poly (ADP-ribose) polymerase family, member 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178685 PARP10 9606 - 8:143977153-144012772 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313028 PARP10-001 143977160-143986454 protein_coding
  ENST00000313059 PARP10-005 143984728-143986430 protein_coding
  ENST00000524918 PARP10-004 143977153-143986446 protein_coding
  ENST00000525486 PARP10-019 143985718-143987181 protein_coding
  ENST00000525773 PARP10-008 143977383-143986460 protein_coding
  ENST00000525879 PARP10-014 143985550-143990933 protein_coding
  ENST00000526007 PARP10-010 143977153-143984358 retained_intron
  ENST00000526985 PARP10-025 143985492-143986141 retained_intron
  ENST00000527262 PARP10-006 143977453-143986422 nonsense_mediated_decay
  ENST00000528136 PARP10-013 143985771-143991039 protein_coding
  ENST00000528580 PARP10-023 143985849-143986460 retained_intron
  ENST00000528625 PARP10-015 143985569-143990269 protein_coding
  ENST00000528914 PARP10-012 143985750-143991135 protein_coding
  ENST00000528963 PARP10-026 143983842-143984639 retained_intron
  ENST00000529311 PARP10-018 143985837-143988965 protein_coding
  ENST00000529842 PARP10-021 143985725-143987099 protein_coding
  ENST00000530478 PARP10-024 143985891-144012772 protein_coding
  ENST00000531537 PARP10-020 143985724-143987144 protein_coding
  ENST00000531707 PARP10-022 143985914-143986932 protein_coding
  ENST00000532311 PARP10-011 143985908-143991188 protein_coding
  ENST00000532660 PARP10-017 143986363-143989985 processed_transcript
  ENST00000533665 PARP10-003 143984983-143986454 processed_transcript
  ENST00000534737 PARP10-016 143986357-143989987 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000313028ENST00000525773ENST00000526007ENST00000527262ENST00000533665
Transcript ID Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000313028 10.794±0.00 N/A N/A 9.216±0.00 0.291±0.00 16.298±13.27 N/A 1.554±0.00 8.485±0.00 25.627±3.95 14.077±2.76
ENST00000525773 N/A N/A 1.563±0.00 N/A N/A N/A N/A 0.615±0.00 N/A 1.214±0.00 N/A
ENST00000526007 N/A 1.877±0.00 N/A 1.077±0.00 N/A N/A 1.140±0.00 N/A 1.157±0.00 N/A N/A
ENST00000527262 N/A 1.392±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000533665 N/A N/A N/A 3.187±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0001 VISTA 8:143880613-144482307
CIL_0002GS CIL_0002GS_0001 CGP 8:143915147-144012772
CIL_0002GF CIL_0002GF_0001 CGP 8:143977153-144012772

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003950 IMP:IEA NAD+ ADP-ribosyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0006471 IMP protein ADP-ribosylation
GO:0008152 IEA metabolic process
GO:0010629 IMP negative regulation of gene expression
GO:0010847 IDA regulation of chromatin assembly
GO:0032088 IMP negative regulation of NF-kappaB transcription factor activity
GO:0033159 IMP negative regulation of protein import into nucleus, translocation
GO:0045071 IMP negative regulation of viral genome replication
GO:0048147 IDA negative regulation of fibroblast proliferation
GO:0070212 IDA protein poly-ADP-ribosylation
GO:0070213 IMP protein auto-ADP-ribosylation
GO:0070530 IMP K63-linked polyubiquitin binding
GO:1900045 IMP negative regulation of protein K63-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087145 PARP10 poly (ADP-ribose) polymerase family, member 10 protein_coding Danio_rerio
ENSMUSG00000063268 Parp10 poly (ADP-ribose) polymerase family, member 10 protein_coding Mus_musculus

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