C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thrombomodulin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178726 THBD 9606 - 20:23045633-23049741 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377103 THBD-001 23045633-23049741 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377103
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377103 15.468±0.00 57.005±0.00 2.058±0.00 1.212±0.98 7.050±4.09 5.531±3.48 4.604±2.46 3.942±2.34 5.207±0.65 26.959±9.99 7.439±1.21 6.535±2.26 19.224±4.46 11.118±7.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OY CIL_0003OY_0001 CGP 20:23035386-23049741
CIL_00023J CIL_00023J_0001 CGP 20:23045633-23086340

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007165 IEA signal transduction
GO:0007565 IEA female pregnancy
GO:0007596 TAS blood coagulation
GO:0009986 IDA cell surface
GO:0010165 IEA response to X-ray
GO:0010544 TAS negative regulation of platelet activation
GO:0016021 IEA integral component of membrane
GO:0030195 TAS negative regulation of blood coagulation
GO:0030246 IEA carbohydrate binding
GO:0032496 IEA response to lipopolysaccharide
GO:0050900 TAS leukocyte migration
GO:0051591 IEA response to cAMP
GO:0051918 TAS negative regulation of fibrinolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000092470 THBD thrombomodulin protein_coding Danio_rerio
ENSMUSG00000074743 Thbd thrombomodulin protein_coding Mus_musculus

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