C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 11, subfamily B, polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179142 CYP11B2 9606 - 8:142910559-142917843 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323110 CYP11B2-001 142910559-142917843 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; TestisENST00000323110
Transcript ID Testis
ENST00000323110 0.081±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00031J CIL_00031J_0001 CGP 8:142834247-142916506
CIL_0002NU CIL_0002NU_0001 CGP 8:142872356-142917843

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002017 IMP regulation of blood volume by renal aldosterone
GO:0003091 IC renal water homeostasis
GO:0004507 IDA steroid 11-beta-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IDA mitochondrion
GO:0005743 IC mitochondrial inner membrane
GO:0006700 IDA C21-steroid hormone biosynthetic process
GO:0006705 TAS mineralocorticoid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 TAS steroid metabolic process
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IC:IEA heme binding
GO:0032342 IDA aldosterone biosynthetic process
GO:0032870 IEP cellular response to hormone stimulus
GO:0034651 IMP cortisol biosynthetic process
GO:0035865 IEP cellular response to potassium ion
GO:0044281 TAS small molecule metabolic process
GO:0047783 IEA corticosterone 18-monooxygenase activity
GO:0055075 IMP potassium ion homeostasis
GO:0055078 IMP sodium ion homeostasis
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042014 cyp11c1 cytochrome P450, family 11, subfamily C, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000022589 Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 protein_coding Mus_musculus
ENSMUSG00000075604 Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 protein_coding Mus_musculus

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