C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cadherin 5, type 2 (vascular endothelium)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179776 CDH5 9606 + 16:66366622-66404786 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341529 CDH5-001 66366630-66404786 protein_coding
  ENST00000539168 CDH5-002 66395455-66403335 protein_coding
  ENST00000562048 CDH5-005 66376341-66386992 protein_coding
  ENST00000563425 CDH5-007 66379225-66392985 protein_coding
  ENST00000565334 CDH5-008 66366690-66403408 nonsense_mediated_decay
  ENST00000568023 CDH5-003 66377209-66379389 protein_coding
  ENST00000568155 CDH5-004 66376390-66386827 protein_coding
  ENST00000614547 CDH5-201 66366622-66404782 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341529ENST00000563425ENST00000565334ENST00000614547
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341529 49.075±0.00 16.693±0.00 0.638±0.00 3.378±3.12 17.177±14.56 9.420±8.70 13.172±11.88 6.447±2.67 1.873±0.14 7.120±0.00 8.076±0.00 4.893±1.96 103.766±57.39 10.774±0.00
ENST00000563425 N/A N/A N/A N/A 1.876±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000565334 N/A N/A 1.438±0.00 0.864±0.00 N/A 1.161±0.00 1.436±0.00 N/A 1.371±0.00 N/A 2.457±0.00 2.098±0.00 N/A N/A
ENST00000614547 16.335±0.00 9.451±0.00 N/A N/A 7.435±0.00 N/A 1.387±0.00 N/A 1.619±0.00 18.198±0.00 2.513±0.00 2.059±0.00 55.554±0.00 3.908±1.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SB CIL_0006SB_0002 CGP 16:64943753-66404786
CIL_0003BQ CIL_0003BQ_0002 CGP 16:66366622-66493529

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001955 IEA blood vessel maturation
GO:0005102 IPI receptor binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 IEA:TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005912 IEA adherens junction
GO:0005923 IEA tight junction
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0008013 IPI beta-catenin binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0016020 IEA:TAS membrane
GO:0016021 IEA integral component of membrane
GO:0019903 IEA protein phosphatase binding
GO:0030054 ISS cell junction
GO:0034329 TAS cell junction assembly
GO:0034332 TAS adherens junction organization
GO:0044325 IPI ion channel binding
GO:0045216 TAS cell-cell junction organization
GO:0071944 IEA cell periphery
GO:2000114 IMP regulation of establishment of cell polarity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075549 cdh5 cadherin 5 protein_coding Danio_rerio
ENSMUSG00000031871 Cdh5 cadherin 5 protein_coding Mus_musculus

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