C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled bile acid receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179921 GPBAR1 9606 + 2:218259496-218263859 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000479077 GPBAR1-001 218259496-218263859 protein_coding
  ENST00000519574 GPBAR1-003 218261015-218263859 protein_coding
  ENST00000521462 GPBAR1-004 218261034-218263848 protein_coding
  ENST00000522678 GPBAR1-002 218261015-218263859 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000479077ENST00000519574ENST00000521462ENST00000522678
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000479077 N/A 0.160±0.00 N/A 0.098±0.00 N/A 0.135±0.00 0.297±0.00 N/A N/A N/A 0.455±0.00 1.041±0.30 0.352±0.19
ENST00000519574 7.830±0.00 0.601±0.00 N/A N/A 9.139±0.00 1.220±0.00 0.711±0.00 0.720±0.00 0.599±0.00 0.412±0.00 0.884±0.54 7.108±0.63 0.569±0.00
ENST00000521462 N/A 0.442±0.00 0.139±0.00 N/A N/A N/A N/A N/A 0.561±0.00 0.652±0.00 1.262±0.00 N/A 0.544±0.00
ENST00000522678 N/A 0.086±0.00 N/A N/A 1.037±0.00 0.076±0.00 0.079±0.00 0.235±0.00 0.122±0.00 0.319±0.00 0.304±0.00 1.362±0.05 0.126±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VL CIL_0005VL_0001 CGP 2:218217094-218263859
CIL_0005VK CIL_0005VK_0001 CGP 2:218259496-218270257

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0038181 IDA bile acid receptor activity
GO:0038182 NAS G-protein coupled bile acid receptor activity
GO:0038184 IC cell surface bile acid receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023302 GPBAR1 (1 of 2) G protein-coupled bile acid receptor 1 protein_coding Danio_rerio
ENSDARG00000092148 GPBAR1 (2 of 2) G protein-coupled bile acid receptor 1 protein_coding Danio_rerio
ENSMUSG00000064272 Gpbar1 G protein-coupled bile acid receptor 1 protein_coding Mus_musculus

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