C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 homeobox 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180053 NKX2-6 9606 - 8:23702451-23706598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000325017 NKX2-6-001 23702451-23706598 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartENST00000325017
Transcript ID Heart
ENST00000325017 0.159±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008FQ CIL_0008FQ_0001 VISTA 8:23193785-23795287
CIL_0007YD CIL_0007YD_0001 VISTA 8:23207989-23809472

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IC nucleus
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007507 IEA heart development
GO:0008284 ISS positive regulation of cell proliferation
GO:0021854 ISS hypothalamus development
GO:0030154 ISS cell differentiation
GO:0035050 ISS embryonic heart tube development
GO:0043066 ISS negative regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0043586 ISS tongue development
GO:0048565 ISS digestive tract development
GO:0055014 ISS atrial cardiac muscle cell development
GO:0055015 ISS ventricular cardiac muscle cell development
GO:0060037 ISS pharyngeal system development
GO:0060039 ISS pericardium development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021232 nkx2.7 NK2 transcription factor related 7 protein_coding Danio_rerio
ENSMUSG00000044186 Nkx2-6 NK2 homeobox 6 protein_coding Mus_musculus

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