C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NAD(P)H dehydrogenase, quinone 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181019 NQO1 9606 - 16:69706996-69726951 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320623 NQO1-001 69709401-69726951 protein_coding
  ENST00000379046 NQO1-004 69710727-69726584 protein_coding
  ENST00000379047 NQO1-002 69709401-69726668 protein_coding
  ENST00000439109 NQO1-007 69710782-69726560 protein_coding
  ENST00000561500 NQO1-003 69706996-69726506 protein_coding
  ENST00000564043 NQO1-005 69710962-69726560 protein_coding
  ENST00000569118 NQO1-006 69717993-69726525 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320623ENST00000379046ENST00000379047ENST00000439109ENST00000561500ENST00000564043ENST00000569118
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320623 N/A N/A 0.516±0.00 0.837±0.00 N/A 2.183±0.00 0.143±0.00 N/A 1.332±1.21 0.523±0.00 N/A N/A 0.372±0.00 0.382±0.00
ENST00000379046 18.777±0.00 N/A 3.178±0.00 3.636±1.62 53.939±0.00 5.145±1.40 1.046±0.25 10.817±10.72 1.840±0.00 3.887±0.00 2.606±0.01 12.383±5.14 2.417±1.24 2.343±0.00
ENST00000379047 11.255±0.00 2.068±0.00 N/A 2.106±0.00 25.780±22.09 4.158±1.38 0.835±0.46 13.290±0.00 0.196±0.00 3.152±2.07 0.734±0.00 4.293±2.45 0.922±0.41 1.949±0.00
ENST00000439109 N/A N/A N/A N/A 2.889±0.00 N/A N/A N/A 1.069±0.00 14.819±0.00 N/A N/A 2.196±0.00 0.557±0.00
ENST00000561500 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.847±0.00
ENST00000564043 52.762±0.00 9.850±0.00 N/A 8.023±5.77 96.636±88.86 12.628±1.31 2.864±1.47 58.992±0.00 1.441±0.78 19.705±18.32 3.469±0.00 28.076±19.86 3.562±1.18 5.363±3.74
ENST00000569118 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 66.915±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KB CIL_0008KB_0001 VISTA 16:69347064-69947578
CIL_0004I1 CIL_0004I1_0001 CGP 16:69565094-69726951
CIL_0004I2 CIL_0004I2_0001 CGP 16:69706996-69754940

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003955 IEA NAD(P)H dehydrogenase (quinone) activity
GO:0004128 TAS cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0004784 IEA superoxide dismutase activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006801 IEA superoxide metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0006809 TAS nitric oxide biosynthetic process
GO:0006979 IEA response to oxidative stress
GO:0007271 TAS synaptic transmission, cholinergic
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0009636 TAS response to toxic substance
GO:0014070 IEA response to organic cyclic compound
GO:0016491 IEA oxidoreductase activity
GO:0019430 IEA removal of superoxide radicals
GO:0032355 IEA response to estradiol
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042802 IPI identical protein binding
GO:0043025 IEA neuronal cell body
GO:0043086 IEA negative regulation of catalytic activity
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045471 IEA response to ethanol
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010250 nqo1 NAD(P)H dehydrogenase, quinone 1 protein_coding Danio_rerio
ENSMUSG00000003849 Nqo1 NAD(P)H dehydrogenase, quinone 1 protein_coding Mus_musculus

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