C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAP2B, member of RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181467 RAP2B 9606 + 3:153162270-153167173 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323534 RAP2B-001 153162270-153167173 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000323534
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000323534 6.782±0.00 6.622±0.00 1.408±0.00 2.758±1.26 5.413±0.60 2.155±0.46 0.914±0.31 2.533±0.33 2.865±1.40 4.252±0.04 0.289±0.08 3.673±0.63 3.574±1.03 2.019±0.72

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004SK CIL_0004SK_0002 CGP 3:152834693-153167173

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005525 IDA:IEA GTP binding
GO:0005622 IEA intracellular
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007165 TAS:IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0015031 IEA protein transport
GO:0016020 IMP:IEA membrane
GO:0019003 IDA GDP binding
GO:0019904 IEA protein domain specific binding
GO:0030168 IDA platelet activation
GO:0030336 IEA negative regulation of cell migration
GO:0031954 IEA positive regulation of protein autophosphorylation
GO:0032486 ISS Rap protein signal transduction
GO:0045121 IMP membrane raft
GO:0055037 IEA recycling endosome
GO:0055038 ISS recycling endosome membrane
GO:0061097 ISS regulation of protein tyrosine kinase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IDA platelet aggregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040296 rap2b RAP2B, member of RAS oncogene family protein_coding Danio_rerio
ENSMUSG00000036894 Rap2b RAP2B, member of RAS oncogene family protein_coding Mus_musculus

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