C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181929 PRKAG1 9606 - 12:49002274-49019197 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316299 PRKAG1-002 49002278-49018779 protein_coding
  ENST00000546531 PRKAG1-008 49002312-49018787 nonsense_mediated_decay
  ENST00000547082 PRKAG1-009 49005311-49018807 protein_coding
  ENST00000547125 PRKAG1-018 49005795-49018757 protein_coding
  ENST00000547306 PRKAG1-006 49002278-49018764 protein_coding
  ENST00000548065 PRKAG1-001 49002281-49019197 protein_coding
  ENST00000548362 PRKAG1-016 49002274-49003593 protein_coding
  ENST00000548605 PRKAG1-014 49005138-49018748 protein_coding
  ENST00000548857 PRKAG1-012 49005131-49018775 protein_coding
  ENST00000548950 PRKAG1-020 49003772-49018750 protein_coding
  ENST00000549726 PRKAG1-004 49003810-49018764 retained_intron
  ENST00000550125 PRKAG1-013 49003757-49018775 retained_intron
  ENST00000550448 PRKAG1-003 49004224-49018764 retained_intron
  ENST00000551121 PRKAG1-019 49003880-49018743 protein_coding
  ENST00000551696 PRKAG1-021 49002969-49018777 protein_coding
  ENST00000551770 PRKAG1-017 49002640-49005835 protein_coding
  ENST00000552212 PRKAG1-005 49002614-49018748 protein_coding
  ENST00000552463 PRKAG1-010 49004572-49018415 protein_coding
  ENST00000552657 PRKAG1-011 49012613-49018786 retained_intron
  ENST00000552793 PRKAG1-015 49003762-49005829 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000316299ENST00000546531ENST00000547306ENST00000548065
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000316299 N/A N/A N/A N/A 5.858±0.00 12.338±0.00 N/A 12.258±0.00 N/A N/A 14.791±0.00 14.672±0.00
ENST00000546531 N/A N/A N/A N/A N/A N/A 5.868±0.00 N/A N/A N/A N/A N/A
ENST00000547306 22.314±0.00 23.209±0.00 9.700±0.00 22.891±0.00 12.028±0.00 12.242±4.04 17.575±0.00 N/A 10.156±0.00 13.945±0.00 13.280±0.00 28.119±0.00
ENST00000548065 N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.977±4.26 12.384±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000E CIL_00000E_0001 CGP 12:48995149-49019197
CIL_00000J CIL_00000J_0001 CGP 12:49002274-49059774

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004679 ISS AMP-activated protein kinase activity
GO:0004691 TAS cAMP-dependent protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006110 TAS regulation of glycolytic process
GO:0006468 IDA protein phosphorylation
GO:0006633 IEA fatty acid biosynthetic process
GO:0007050 TAS cell cycle arrest
GO:0007165 TAS signal transduction
GO:0007283 TAS spermatogenesis
GO:0008286 TAS insulin receptor signaling pathway
GO:0008603 TAS cAMP-dependent protein kinase regulator activity
GO:0010628 IDA positive regulation of gene expression
GO:0016020 IDA membrane
GO:0016208 ISS AMP binding
GO:0019901 IDA protein kinase binding
GO:0030554 IEA adenyl nucleotide binding
GO:0031588 ISS AMP-activated protein kinase complex
GO:0043234 IEA protein complex
GO:0043531 ISS ADP binding
GO:0045860 TAS positive regulation of protein kinase activity
GO:0050790 IEA regulation of catalytic activity
GO:0051291 IEA protein heterooligomerization
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003818 prkag1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit protein_coding Danio_rerio
ENSMUSG00000067713 Prkag1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit protein_coding Mus_musculus

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