C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: epithelial mitogen
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182585 EPGN 9606 + 4:74308473-74315307 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332112 EPGN-003 74308487-74313590 protein_coding
  ENST00000413830 EPGN-001 74308473-74315307 protein_coding
  ENST00000446430 EPGN-009 74309097-74314984 protein_coding
  ENST00000502358 EPGN-006 74308534-74314637 protein_coding
  ENST00000502835 EPGN-002 74308474-74314670 nonsense_mediated_decay
  ENST00000503098 EPGN-005 74308534-74314637 protein_coding
  ENST00000505212 EPGN-008 74308534-74314637 protein_coding
  ENST00000509145 EPGN-007 74308534-74314637 protein_coding
  ENST00000514968 EPGN-004 74308534-74314637 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartKidneyOvaryPlacentaTestisENST00000413830ENST00000446430ENST00000502358ENST00000502835ENST00000509145
Transcript ID Adrenal Brain Breast Heart Kidney Ovary Placenta Testis
ENST00000413830 0.018±0.00 0.032±0.00 N/A 0.010±0.00 N/A 0.294±0.17 0.212±0.15 0.113±0.00
ENST00000446430 N/A N/A 0.245±0.00 N/A 1.001±0.00 0.318±0.00 0.088±0.00 N/A
ENST00000502358 N/A N/A N/A N/A N/A N/A 0.609±0.00 N/A
ENST00000502835 N/A N/A N/A 0.026±0.00 N/A N/A N/A N/A
ENST00000509145 N/A N/A N/A 0.089±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SN CIL_0006SN_0001 CGP 4:74114174-74315307
CIL_0006SO CIL_0006SO_0001 CGP 4:74308473-74388751

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000187 ISS activation of MAPK activity
GO:0001525 IDA angiogenesis
GO:0005154 IDA epidermal growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005887 IDA integral component of plasma membrane
GO:0008083 IDA growth factor activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0045741 IDA positive regulation of epidermal growth factor-activated receptor activity
GO:0045840 IDA positive regulation of mitosis
GO:0050679 ISS positive regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000035020 Epgn epithelial mitogen protein_coding Mus_musculus

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