C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: annexin A2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182718 ANXA2 9606 - 15:60347134-60402883 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332680 ANXA2-006 60347332-60397985 protein_coding
  ENST00000396024 ANXA2-001 60347134-60397986 protein_coding
  ENST00000421017 ANXA2-005 60347342-60397986 protein_coding
  ENST00000451270 ANXA2-002 60347327-60398043 protein_coding
  ENST00000504475 ANXA2-008 60347337-60384827 retained_intron
  ENST00000557904 ANXA2-038 60364429-60402883 protein_coding
  ENST00000557906 ANXA2-019 60355919-60397986 protein_coding
  ENST00000557937 ANXA2-017 60362627-60397986 processed_transcript
  ENST00000557986 ANXA2-030 60393097-60397973 protein_coding
  ENST00000558132 ANXA2-025 60351782-60397986 protein_coding
  ENST00000558169 ANXA2-013 60382348-60397988 protein_coding
  ENST00000558503 ANXA2-029 60354153-60397974 nonsense_mediated_decay
  ENST00000558558 ANXA2-021 60357191-60397986 protein_coding
  ENST00000558985 ANXA2-010 60351724-60398033 protein_coding
  ENST00000558986 ANXA2-035 60357194-60391151 protein_coding
  ENST00000558998 ANXA2-033 60354154-60397964 protein_coding
  ENST00000559113 ANXA2-024 60355919-60397986 protein_coding
  ENST00000559176 ANXA2-037 60351192-60374505 protein_coding
  ENST00000559350 ANXA2-036 60357146-60391127 protein_coding
  ENST00000559370 ANXA2-016 60364476-60397986 protein_coding
  ENST00000559467 ANXA2-027 60360941-60397978 protein_coding
  ENST00000559559 ANXA2-003 60355428-60397988 retained_intron
  ENST00000559647 ANXA2-039 60349075-60351553 retained_intron
  ENST00000559725 ANXA2-011 60355961-60398001 protein_coding
  ENST00000559780 ANXA2-028 60360942-60397974 protein_coding
  ENST00000559818 ANXA2-009 60351733-60398742 protein_coding
  ENST00000559956 ANXA2-026 60360941-60397984 protein_coding
  ENST00000560014 ANXA2-007 60347337-60387097 nonsense_mediated_decay
  ENST00000560165 ANXA2-031 60355919-60397968 protein_coding
  ENST00000560367 ANXA2-032 60352383-60397338 protein_coding
  ENST00000560389 ANXA2-034 60355919-60391297 protein_coding
  ENST00000560466 ANXA2-023 60351733-60397986 protein_coding
  ENST00000560468 ANXA2-020 60360967-60397986 protein_coding
  ENST00000560495 ANXA2-012 60395907-60397988 processed_transcript
  ENST00000560546 ANXA2-015 60385557-60397986 retained_intron
  ENST00000560936 ANXA2-014 60395645-60397986 processed_transcript
  ENST00000561022 ANXA2-022 60351787-60397986 nonsense_mediated_decay
  ENST00000561445 ANXA2-018 60361448-60397986 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000332680ENST00000421017ENST00000451270ENST00000558132ENST00000559176ENST00000560466
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000332680 N/A N/A N/A 0.832±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 170.058±0.00 N/A
ENST00000421017 41.820±0.00 41.565±0.00 N/A 1.013±0.00 91.760±0.00 21.402±0.00 2.568±0.00 21.109±0.00 4.854±0.00 N/A N/A 19.876±0.00 104.374±0.00 22.035±0.00
ENST00000451270 148.013±0.00 118.273±0.00 7.135±0.00 6.964±6.22 183.875±127.62 66.482±23.74 28.145±21.12 94.988±0.00 30.143±10.45 229.816±146.94 22.522±9.15 96.196±17.56 211.692±29.19 79.871±0.00
ENST00000558132 N/A N/A 22.000±0.00 6.498±0.00 146.784±0.00 142.945±0.00 17.056±0.00 12.478±0.00 105.211±0.00 166.179±0.00 34.125±0.00 249.400±0.00 N/A N/A
ENST00000559176 N/A N/A N/A N/A N/A N/A N/A 5.293±0.00 N/A N/A N/A N/A N/A N/A
ENST00000560466 N/A N/A N/A N/A N/A 37.660±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007LQ CIL_0007LQ_0001 UCNEbase 15:59905203-60532122

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEP angiogenesis
GO:0001726 IEA ruffle
GO:0001765 IMP membrane raft assembly
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004859 IEA phospholipase inhibitor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005544 IEA:IDA calcium-dependent phospholipid binding
GO:0005546 IMP phosphatidylinositol-4,5-bisphosphate binding
GO:0005604 IEA basement membrane
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005765 IDA lysosomal membrane
GO:0005768 IDA endosome
GO:0005769 IEA early endosome
GO:0005811 IDA lipid particle
GO:0005886 IDA plasma membrane
GO:0005938 IEA cell cortex
GO:0006900 IMP membrane budding
GO:0007589 IEA body fluid secretion
GO:0008092 IEA cytoskeletal protein binding
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0017137 IEA Rab GTPase binding
GO:0019834 IDA phospholipase A2 inhibitor activity
GO:0019897 IEA extrinsic component of plasma membrane
GO:0030199 IEA collagen fibril organization
GO:0030496 IDA midbody
GO:0031012 ISS extracellular matrix
GO:0031340 IDA positive regulation of vesicle fusion
GO:0031902 IDA late endosome membrane
GO:0031982 IDA vesicle
GO:0035749 IEA myelin sheath adaxonal region
GO:0036035 IDA osteoclast development
GO:0042383 IEA sarcolemma
GO:0042730 IEA fibrinolysis
GO:0043086 IEA negative regulation of catalytic activity
GO:0043220 IEA Schmidt-Lanterman incisure
GO:0043234 IEA protein complex
GO:0044354 IEA macropinosome
GO:0044548 IPI S100 protein binding
GO:0044822 IDA poly(A) RNA binding
GO:0045121 IDA membrane raft
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048306 IPI calcium-dependent protein binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051099 IEA positive regulation of binding
GO:0051290 IDA protein heterotetramerization
GO:0070062 IDA extracellular vesicular exosome
GO:0072661 IEA protein targeting to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003216 anxa2a annexin A2a protein_coding Danio_rerio
ENSDARG00000053625 anxa2b annexin A2b protein_coding Danio_rerio
ENSMUSG00000032231 Anxa2 annexin A2 protein_coding Mus_musculus

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