C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of G-protein signaling 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182732 RGS6 9606 + 14:71932439-72566529 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343854 RGS6-201 72352093-72566529 protein_coding
  ENST00000355512 RGS6-006 71964792-72537713 protein_coding
  ENST00000402788 RGS6-202 72352092-72566529 protein_coding
  ENST00000404301 RGS6-010 71964792-72540324 protein_coding
  ENST00000406236 RGS6-011 71964792-72540324 protein_coding
  ENST00000407322 RGS6-012 71964792-72540333 protein_coding
  ENST00000434263 RGS6-007 72454520-72550674 protein_coding
  ENST00000553519 RGS6-013 72511607-72515847 processed_transcript
  ENST00000553525 RGS6-001 71932439-72562476 protein_coding
  ENST00000553530 RGS6-003 71933116-72566526 protein_coding
  ENST00000553690 RGS6-009 72420979-72474069 processed_transcript
  ENST00000554300 RGS6-016 72540062-72562837 processed_transcript
  ENST00000554474 RGS6-004 71933145-72562864 nonsense_mediated_decay
  ENST00000554734 RGS6-015 72473987-72477260 retained_intron
  ENST00000554782 RGS6-008 72459669-72562754 protein_coding
  ENST00000555368 RGS6-014 72454520-72478331 processed_transcript
  ENST00000555571 RGS6-002 71932617-72562467 protein_coding
  ENST00000556437 RGS6-005 71933232-72562592 protein_coding
  ENST00000622468 RGS6-203 72352093-72566529 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343854ENST00000402788ENST00000406236ENST00000434263ENST00000553519ENST00000553525ENST00000553530ENST00000554300ENST00000554474ENST00000554782ENST00000555571ENST00000556437ENST00000622468
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343854 0.882±0.00 N/A N/A 1.405±0.00 0.265±0.00 1.069±0.00 N/A 0.072±0.00 N/A N/A N/A N/A 0.433±0.00 0.839±0.00
ENST00000402788 1.368±0.00 0.053±0.00 N/A 1.576±1.06 N/A N/A 3.061±0.00 0.104±0.00 N/A 0.450±0.00 N/A 0.061±0.00 0.696±0.00 N/A
ENST00000406236 N/A N/A N/A 2.369±0.00 N/A N/A N/A N/A N/A 0.714±0.00 N/A 0.393±0.00 N/A 3.426±2.50
ENST00000434263 N/A N/A N/A N/A N/A 0.137±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000553519 0.029±0.00 N/A N/A 0.102±0.00 0.099±0.00 N/A 0.145±0.00 N/A N/A N/A 0.907±0.00 N/A N/A 0.562±0.45
ENST00000553525 1.679±0.00 N/A N/A N/A 0.514±0.00 2.193±0.00 0.382±0.00 N/A N/A N/A N/A N/A 1.025±0.66 N/A
ENST00000553530 N/A N/A N/A 0.579±0.00 N/A N/A 0.284±0.00 N/A 0.124±0.00 N/A N/A N/A N/A N/A
ENST00000554300 N/A 1.309±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.009±0.00 N/A N/A N/A
ENST00000554474 N/A N/A 0.326±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000554782 N/A 0.125±0.00 N/A N/A 0.328±0.00 N/A N/A N/A 0.012±0.00 N/A 0.297±0.00 0.047±0.00 0.434±0.00 3.216±1.55
ENST00000555571 2.456±0.00 0.112±0.00 N/A N/A 0.429±0.00 N/A 2.612±0.00 0.266±0.00 N/A 0.720±0.00 N/A N/A N/A 1.042±0.00
ENST00000556437 N/A N/A 0.373±0.00 1.306±0.00 N/A 0.639±0.00 N/A N/A 0.466±0.00 N/A 0.088±0.00 0.305±0.01 N/A N/A
ENST00000622468 N/A 0.036±0.00 N/A N/A 0.652±0.00 N/A N/A N/A N/A N/A N/A 0.161±0.00 0.151±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 IEA signal transducer activity
GO:0005096 IBA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IBA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005834 IEA heterotrimeric G-protein complex
GO:0005886 IBA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0019904 IEA protein domain specific binding
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043234 IEA protein complex
GO:0043547 IBA positive regulation of GTPase activity
GO:0045666 IEA positive regulation of neuron differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015627 rgs6 regulator of G-protein signalling 6 protein_coding Danio_rerio
ENSMUSG00000021219 Rgs6 regulator of G-protein signaling 6 protein_coding Mus_musculus

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