C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pregnancy-associated plasma protein A, pappalysin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182752 PAPPA 9606 + 9:116153804-116402322 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328252 PAPPA-001 116153804-116402322 protein_coding
  ENST00000460463 PAPPA-002 116332432-116335074 processed_transcript
  ENST00000483254 PAPPA-003 116373199-116396616 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000328252
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000328252 0.301±0.00 0.372±0.00 0.844±0.00 0.053±0.00 0.226±0.20 0.457±0.29 0.280±0.00 0.860±0.70 0.287±0.27 0.359±0.00 0.020±0.01 0.315±0.17 66.745±43.87 0.508±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008GA CIL_0008GA_0001 VISTA 9:115971136-116573178
CIL_0004FO CIL_0004FO_0001 CGP 9:116153804-117415070

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 IEA endopeptidase activity
GO:0005515 IEA protein binding
GO:0005576 IDA extracellular region
GO:0006508 IEA proteolysis
GO:0007565 NAS female pregnancy
GO:0008237 IDA metallopeptidase activity
GO:0008270 NAS zinc ion binding
GO:0016020 IEA membrane
GO:0030154 IEA cell differentiation
GO:0044267 TAS cellular protein metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059544 pappaa pregnancy-associated plasma protein A, pappalysin 1a protein_coding Danio_rerio
ENSDARG00000059858 pappab pregnancy-associated plasma protein A, pappalysin 1b protein_coding Danio_rerio
ENSMUSG00000028370 Pappa pregnancy-associated plasma protein A protein_coding Mus_musculus

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