C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184545 DUSP8 9606 - 11:1554044-1571920 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331588 DUSP8-201 1554051-1565936 protein_coding
  ENST00000397374 DUSP8-001 1554044-1571920 protein_coding
  ENST00000528778 DUSP8-002 1557523-1559443 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331588ENST00000397374ENST00000528778
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331588 2.773±0.00 1.079±0.00 0.060±0.00 12.949±0.00 1.054±0.89 1.372±0.00 3.536±0.00 0.126±0.12 0.054±0.00 0.030±0.00 3.960±0.00 1.378±0.79 1.254±0.55 1.855±1.49
ENST00000397374 N/A N/A N/A 1.036±0.00 N/A N/A 1.813±0.00 0.410±0.40 N/A N/A 2.184±0.00 1.200±0.00 1.190±0.00 0.358±0.00
ENST00000528778 N/A N/A N/A 3.619±0.00 0.484±0.00 N/A N/A N/A N/A 4.167±3.82 0.888±0.00 7.774±5.12 N/A 1.265±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MR CIL_0005MR_0002 CGP 11:1469457-1571920

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 TAS inactivation of MAPK activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0006470 IBA:IEA protein dephosphorylation
GO:0008138 IBA:IEA protein tyrosine/serine/threonine phosphatase activity
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0017017 IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009299 dusp8a dual specificity phosphatase 8a protein_coding Danio_rerio
ENSDARG00000039232 DUSP8 (2 of 2) dual specificity phosphatase 8 protein_coding Danio_rerio
ENSMUSG00000037887 Dusp8 dual specificity phosphatase 8 protein_coding Mus_musculus

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