C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, muscarinic 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184984 CHRM5 9606 + 15:33968720-34067457 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000383263 CHRM5-001 33968888-34067457 protein_coding
  ENST00000557872 CHRM5-002 34018227-34065090 protein_coding
  ENST00000560035 CHRM5-003 33968720-34062783 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000383263ENST00000557872ENST00000560035
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000383263 N/A N/A 0.054±0.00 0.024±0.01 N/A 0.016±0.00 N/A 0.014±0.00 N/A 0.033±0.02 0.531±0.27 0.065±0.00
ENST00000557872 0.018±0.00 0.213±0.00 0.060±0.00 N/A 0.107±0.00 0.020±0.00 0.154±0.14 0.005±0.00 0.013±0.00 0.102±0.04 1.504±0.48 0.303±0.08
ENST00000560035 N/A N/A 2.596±2.35 N/A N/A 0.154±0.00 0.953±0.00 0.544±0.00 0.973±0.00 0.027±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001696 IEA gastric acid secretion
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007197 TAS adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
GO:0007213 TAS G-protein coupled acetylcholine receptor signaling pathway
GO:0008152 TAS metabolic process
GO:0008283 TAS cell proliferation
GO:0015872 IEA dopamine transport
GO:0016021 IEA integral component of membrane
GO:0016907 IEA G-protein coupled acetylcholine receptor activity
GO:0019226 IEA transmission of nerve impulse
GO:0030054 IEA cell junction
GO:0045211 IEA postsynaptic membrane
GO:0060304 IEA regulation of phosphatidylinositol dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004026 chrm5a cholinergic receptor, muscarinic 5a protein_coding Danio_rerio
ENSDARG00000069598 chrm5b cholinergic receptor, muscarinic 5b protein_coding Danio_rerio
ENSMUSG00000074939 Chrm5 cholinergic receptor, muscarinic 5 protein_coding Mus_musculus

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