C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SIVA1, apoptosis-inducing factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184990 SIVA1 9606 + 14:104753100-104768494 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000329967 SIVA1-001 104753100-104759657 protein_coding
  ENST00000347067 SIVA1-002 104753159-104759659 protein_coding
  ENST00000535554 SIVA1-004 104753147-104757479 retained_intron
  ENST00000553810 SIVA1-007 104753160-104757312 protein_coding
  ENST00000553819 SIVA1-008 104753171-104768494 nonsense_mediated_decay
  ENST00000554013 SIVA1-006 104753181-104756925 retained_intron
  ENST00000556195 SIVA1-005 104753718-104759578 protein_coding
  ENST00000556431 SIVA1-003 104753202-104759653 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000329967ENST00000347067ENST00000553810ENST00000553819ENST00000556195ENST00000556431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000329967 13.850±0.00 21.395±0.00 N/A 4.019±0.68 12.217±10.41 23.645±0.00 9.524±8.82 10.914±4.87 21.512±0.00 15.322±14.50 14.403±0.00 32.791±25.25 59.254±37.52 37.647±0.00
ENST00000347067 N/A 11.198±0.00 0.831±0.00 1.619±0.00 1.094±0.00 16.030±0.00 1.122±0.00 N/A N/A N/A N/A 10.439±8.88 23.897±0.00 34.766±18.76
ENST00000553810 7.630±0.00 16.517±0.00 N/A 6.959±0.00 17.679±0.00 24.557±0.00 13.197±0.00 12.423±0.00 N/A 33.888±0.00 6.710±0.00 14.203±0.00 30.288±0.00 39.079±11.13
ENST00000553819 N/A N/A N/A N/A N/A N/A N/A N/A 3.179±2.58 N/A N/A N/A N/A N/A
ENST00000556195 N/A N/A N/A 6.049±0.00 N/A N/A N/A N/A N/A N/A 5.053±0.00 N/A N/A N/A
ENST00000556431 N/A N/A N/A 0.191±0.00 N/A 0.159±0.00 N/A 0.642±0.10 0.956±0.00 N/A 0.853±0.44 2.047±0.67 N/A 2.812±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00059G CIL_00059G_0002 CGP 14:104724186-104768494
CIL_0001G0 CIL_0001G0_0001 CGP 14:104753100-104795751

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001618 ISS virus receptor activity
GO:0005175 IPI CD27 receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006924 IDA activation-induced cell death of T cells
GO:0008270 IDA zinc ion binding
GO:0009615 ISS response to virus
GO:0016032 IEA viral process
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0046872 IEA metal ion binding
GO:0097191 IDA extrinsic apoptotic signaling pathway
GO:0097193 IDA intrinsic apoptotic signaling pathway
GO:1901030 IDA positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086639 siva1 SIVA1, apoptosis-inducing factor protein_coding Danio_rerio
ENSMUSG00000059830 Gm16380 predicted pseudogene 16380 protein_coding Mus_musculus
ENSMUSG00000064326 Siva1 SIVA1, apoptosis-inducing factor protein_coding Mus_musculus

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