C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fas (TNFRSF6) associated factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185104 FAF1 9606 - 1:50439478-50960263 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371778 FAF1-201 50441276-50959793 protein_coding
  ENST00000396153 FAF1-001 50439478-50960263 protein_coding
  ENST00000472808 FAF1-005 50539592-50606944 processed_transcript
  ENST00000487898 FAF1-004 50705784-50959738 processed_transcript
  ENST00000494400 FAF1-002 50441276-50706051 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371778ENST00000396153ENST00000472808ENST00000487898ENST00000494400
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371778 3.517±0.00 7.426±0.00 N/A 6.989±3.45 9.069±0.00 11.030±0.00 10.999±0.00 6.410±4.92 4.254±0.00 6.436±0.00 39.766±0.00 10.295±2.17 9.270±4.96 43.550±25.21
ENST00000396153 1.342±0.00 1.820±0.00 N/A 2.479±0.10 2.644±0.10 2.002±0.47 4.105±2.35 2.059±0.00 2.225±1.36 1.355±0.52 7.827±6.12 2.304±1.15 1.830±0.57 5.921±0.00
ENST00000472808 N/A N/A 3.015±0.00 9.736±0.00 4.614±0.00 5.937±0.00 2.722±0.00 2.719±0.00 N/A 3.711±0.00 4.225±0.00 N/A N/A N/A
ENST00000487898 N/A N/A N/A 6.805±0.00 8.059±0.00 9.591±0.00 6.171±0.00 4.337±0.00 11.201±0.00 11.339±0.00 8.129±0.00 7.448±0.00 N/A N/A
ENST00000494400 N/A 2.005±0.00 N/A 2.906±0.00 1.489±0.32 2.632±0.00 1.361±0.00 2.023±0.00 N/A 2.601±0.98 2.283±0.00 3.702±0.31 4.621±0.44 19.112±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K0 CIL_0008K0_0001 VISTA 1:50240418-50841642
CIL_0008UT CIL_0008UT_0001 VISTA 1:50268874-50870617
CIL_0008US CIL_0008US_0001 VISTA 1:50333169-50934241
CIL_0009AC CIL_0009AC_0001 VISTA 1:50399523-51001114
CIL_00063F CIL_00063F_0002 CGP 1:50417550-50960263
CIL_0006WA CIL_0006WA_0002 CGP 1:50439478-50974633

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005635 IEA nuclear envelope
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006915 IEA apoptotic process
GO:0007253 IMP cytoplasmic sequestering of NF-kappaB
GO:0008219 IMP cell death
GO:0019887 NAS protein kinase regulator activity
GO:0019901 IDA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030155 IEA regulation of cell adhesion
GO:0031072 IDA heat shock protein binding
GO:0031265 NAS CD95 death-inducing signaling complex
GO:0031334 IMP positive regulation of protein complex assembly
GO:0031625 IDA ubiquitin protein ligase binding
GO:0034098 IDA Cdc48p-Npl4p-Ufd1p AAA ATPase complex
GO:0042176 IMP regulation of protein catabolic process
GO:0043065 NAS positive regulation of apoptotic process
GO:0043130 IDA ubiquitin binding
GO:0043161 NAS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045859 NAS regulation of protein kinase activity
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051059 IPI NF-kappaB binding
GO:1902043 IEA positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022418 faf1 Fas associated factor 1 protein_coding Danio_rerio
ENSMUSG00000010517 Faf1 Fas-associated factor 1 protein_coding Mus_musculus

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