C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Mix paired-like homeobox
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185155 MIXL1 9606 + 1:226223618-226227054 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366810 MIXL1-001 226223618-226227054 protein_coding
  ENST00000542034 MIXL1-002 226223618-226225864 protein_coding
  ENST00000557734 MIXL1-003 226225503-226226389 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLungOvaryPlacentaTestisENST00000366810ENST00000542034ENST00000557734
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Lung Ovary Placenta Testis
ENST00000366810 0.056±0.00 N/A 0.142±0.02 0.079±0.00 0.008±0.00 0.122±0.00 0.207±0.00 0.177±0.00 0.057±0.03 0.459±0.32
ENST00000542034 0.055±0.00 N/A N/A N/A N/A N/A N/A N/A 0.124±0.00 0.502±0.00
ENST00000557734 N/A 0.188±0.00 N/A N/A N/A N/A 0.076±0.00 0.110±0.04 0.299±0.00 0.348±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000BW CIL_0000BW_0002 CGP 1:226223618-226309869

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 ISS nuclear chromatin
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 ISS RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000987 ISS core promoter proximal region sequence-specific DNA binding
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 ISS RNA polymerase II transcription factor binding
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001190 ISS RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001205 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001706 IEA endoderm formation
GO:0002244 ISS hematopoietic progenitor cell differentiation
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007369 ISS gastrulation
GO:0007492 ISS endoderm development
GO:0007507 ISS heart development
GO:0030097 IEA hemopoiesis
GO:0035987 ISS endodermal cell differentiation
GO:0042074 IEA cell migration involved in gastrulation
GO:0042803 ISS protein homodimerization activity
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048565 ISS digestive tract development
GO:1901533 ISS negative regulation of hematopoietic progenitor cell differentiation
GO:2000382 ISS positive regulation of mesoderm development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009737 bon bonnie and clyde protein_coding Danio_rerio
ENSDARG00000015906 mxtx2 mix-type homeobox gene 2 protein_coding Danio_rerio
ENSDARG00000069252 bon bonnie and clyde protein_coding Danio_rerio
ENSDARG00000069382 mxtx1 mix-type homeobox gene 1 protein_coding Danio_rerio
ENSMUSG00000026497 Mixl1 Mix1 homeobox-like 1 (Xenopus laevis) protein_coding Mus_musculus

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