C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon induced transmembrane protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185201 IFITM2 9606 + 11:307631-315272 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000399815 IFITM2-004 308408-315272 protein_coding
  ENST00000399817 IFITM2-001 308163-309395 protein_coding
  ENST00000527146 IFITM2-002 308320-309392 nonsense_mediated_decay
  ENST00000533141 IFITM2-003 307631-309230 protein_coding
  ENST00000602569 IFITM2-005 308217-309395 protein_coding
  ENST00000616316 IFITM2-201 307927-309392 protein_coding
  ENST00000619184 IFITM2-202 307927-309392 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000399817ENST00000527146ENST00000533141ENST00000602569ENST00000616316
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000399817 125.430±0.00 228.629±0.00 N/A 10.554±8.10 67.631±0.00 154.781±0.00 34.251±31.68 137.623±0.00 165.550±0.00 241.720±238.53 53.054±0.00 116.365±78.21 108.215±65.20 47.653±40.16
ENST00000527146 N/A N/A N/A N/A N/A N/A N/A 6.055±0.00 N/A N/A N/A N/A N/A N/A
ENST00000533141 N/A N/A 1.889±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000602569 316.410±0.00 327.739±0.00 2.983±0.00 52.077±0.00 89.078±0.00 261.764±0.00 68.482±0.00 212.826±0.00 498.232±0.00 1058.490±0.00 26.053±24.09 172.805±77.83 273.287±117.24 82.721±57.29
ENST00000616316 N/A N/A N/A N/A N/A N/A N/A 4.403±0.00 N/A 1.913±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UF CIL_0002UF_0001 CGP 11:298200-315272
CIL_0002UG CIL_0002UG_0001 CGP 11:307631-315272

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005886 TAS plasma membrane
GO:0006955 TAS immune response
GO:0009607 IEA response to biotic stimulus
GO:0009615 IDA response to virus
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0034341 IDA response to interferon-gamma
GO:0035455 IDA response to interferon-alpha
GO:0035456 IDA response to interferon-beta
GO:0045071 IDA negative regulation of viral genome replication
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000093303 si:dkey-226m8.7 interferon induced transmembrane protein 3 protein_coding Danio_rerio
ENSMUSG00000025491 Ifitm1 interferon induced transmembrane protein 1 protein_coding Mus_musculus
ENSMUSG00000025492 Ifitm3 interferon induced transmembrane protein 3 protein_coding Mus_musculus
ENSMUSG00000060591 Ifitm2 interferon induced transmembrane protein 2 protein_coding Mus_musculus
ENSMUSG00000065968 Ifitm7 interferon induced transmembrane protein 7 protein_coding Mus_musculus
ENSMUSG00000068631 Gm7676 predicted gene 7676 protein_coding Mus_musculus

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