C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Sp1 transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185591 SP1 9606 + 12:53380176-53416446 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327443 SP1-001 53380194-53411630 protein_coding
  ENST00000426431 SP1-002 53380639-53416446 protein_coding
  ENST00000548560 SP1-004 53381302-53382658 protein_coding
  ENST00000551969 SP1-003 53380176-53382577 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000327443ENST00000426431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000327443 N/A N/A 1.315±0.00 0.573±0.00 N/A N/A 1.115±0.00 1.419±0.00 3.239±0.00 N/A N/A 3.224±0.00 N/A 2.907±0.00
ENST00000426431 16.692±0.00 7.278±0.00 1.742±0.00 2.722±2.39 5.685±2.36 4.329±2.15 2.642±0.72 7.675±0.00 3.765±2.21 8.166±0.18 7.329±3.54 7.206±5.52 5.614±0.58 12.981±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00060O CIL_00060O_0001 CGP 12:53326575-53416446
CIL_0001W1 CIL_0001W1_0001 CGP 12:53380176-53431534

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 IEA core promoter proximal region sequence-specific DNA binding
GO:0001046 ISS core promoter sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001103 ISS RNA polymerase II repressing transcription factor binding
GO:0001503 IEA ossification
GO:0001701 IEA in utero embryonic development
GO:0001829 IEA trophectodermal cell differentiation
GO:0001889 IEA liver development
GO:0001892 IEA embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008022 IPI protein C-terminus binding
GO:0008134 IPI transcription factor binding
GO:0010467 TAS gene expression
GO:0016032 IEA viral process
GO:0030219 IEA megakaryocyte differentiation
GO:0030324 IEA lung development
GO:0032993 IEA protein-DNA complex
GO:0035035 IEA histone acetyltransferase binding
GO:0035326 IEA enhancer binding
GO:0042803 IDA protein homodimerization activity
GO:0042826 IPI histone deacetylase binding
GO:0043353 IEA enucleate erythrocyte differentiation
GO:0043425 ISS bHLH transcription factor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0043923 IDA positive regulation by host of viral transcription
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048511 IEA rhythmic process
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0060136 IEA embryonic process involved in female pregnancy
GO:0060216 IEA definitive hemopoiesis
GO:0071837 IPI HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088347 sp1 sp1 transcription factor protein_coding Danio_rerio
ENSMUSG00000001280 Sp1 trans-acting transcription factor 1 protein_coding Mus_musculus

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