C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein disulfide isomerase family A, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185615 PDIA2 9606 + 16:283152-287215 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219406 PDIA2-001 283152-287215 protein_coding
  ENST00000404312 PDIA2-008 283165-287114 protein_coding
  ENST00000435833 PDIA2-007 285680-287215 protein_coding
  ENST00000456379 PDIA2-005 283180-285140 protein_coding
  ENST00000462950 PDIA2-006 284875-285576 processed_transcript
  ENST00000467212 PDIA2-003 283164-287214 retained_intron
  ENST00000482665 PDIA2-004 284152-287208 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000219406ENST00000404312ENST00000435833ENST00000456379ENST00000482665
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000219406 N/A N/A 1.673±0.00 0.117±0.00 N/A N/A N/A N/A 0.062±0.00 1.224±0.00 N/A
ENST00000404312 0.183±0.00 N/A 2.189±0.00 0.062±0.00 0.160±0.00 0.111±0.00 N/A N/A N/A 0.834±0.00 0.270±0.08
ENST00000435833 0.063±0.00 0.089±0.00 N/A 0.139±0.00 0.248±0.00 N/A N/A N/A 0.103±0.05 0.530±0.10 0.302±0.00
ENST00000456379 N/A 0.207±0.00 1.903±0.00 0.254±0.00 N/A N/A N/A 0.195±0.00 N/A N/A N/A
ENST00000482665 N/A N/A 0.838±0.33 N/A N/A N/A 0.044±0.00 0.109±0.00 0.141±0.06 0.299±0.00 0.156±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00094P CIL_00094P_0001 VISTA 16:-195470-405616
CIL_0008HK CIL_0008HK_0001 VISTA 16:-187027-414801

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003756 IBA protein disulfide isomerase activity
GO:0005496 IEA steroid binding
GO:0005515 IPI protein binding
GO:0005783 IBA:IEA endoplasmic reticulum
GO:0006457 IBA protein folding
GO:0006621 TAS protein retention in ER lumen
GO:0008152 IEA metabolic process
GO:0016209 IEA antioxidant activity
GO:0016491 IEA oxidoreductase activity
GO:0016853 IEA isomerase activity
GO:0019511 IBA peptidyl-proline hydroxylation
GO:0031545 IBA peptidyl-proline 4-dioxygenase activity
GO:0034976 IBA response to endoplasmic reticulum stress
GO:0045454 IEA cell redox homeostasis
GO:0055114 IEA oxidation-reduction process
GO:1902175 IBA regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018263 pdia2 protein disulfide isomerase family A, member 2 protein_coding Danio_rerio
ENSMUSG00000024184 Pdia2 protein disulfide isomerase associated 2 protein_coding Mus_musculus

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