C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: purinergic receptor P2X, ligand-gated ion channel, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000187848 P2RX2 9606 + 12:132618780-132622386 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343948 P2RX2-003 132618817-132621972 protein_coding
  ENST00000348800 P2RX2-010 132618817-132621979 protein_coding
  ENST00000350048 P2RX2-009 132618817-132621972 protein_coding
  ENST00000351222 P2RX2-008 132618817-132621972 protein_coding
  ENST00000352418 P2RX2-007 132618817-132621972 protein_coding
  ENST00000389110 P2RX2-006 132618780-132622386 protein_coding
  ENST00000449132 P2RX2-001 132618817-132621972 protein_coding
  ENST00000542301 P2RX2-002 132618817-132622340 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000343948ENST00000348800ENST00000351222ENST00000389110ENST00000449132ENST00000542301
Transcript ID Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000343948 N/A N/A N/A N/A N/A N/A N/A N/A 1.925±0.00
ENST00000348800 N/A N/A 0.654±0.00 N/A 0.020±0.00 N/A 0.143±0.09 0.129±0.00 0.374±0.00
ENST00000351222 0.469±0.00 0.054±0.00 N/A 0.968±0.00 N/A 1.033±0.00 N/A 0.314±0.00 N/A
ENST00000389110 N/A N/A N/A N/A N/A N/A N/A 0.127±0.08 N/A
ENST00000449132 0.295±0.00 N/A N/A N/A N/A N/A 0.051±0.00 N/A N/A
ENST00000542301 N/A N/A N/A N/A N/A N/A 0.029±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001614 NAS:IEA purinergic nucleotide receptor activity
GO:0001666 IEA response to hypoxia
GO:0003029 IEA detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
GO:0004931 NAS extracellular ATP-gated cation channel activity
GO:0005216 IEA ion channel activity
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005524 NAS:IEA ATP binding
GO:0005622 IEA intracellular
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005886 IEA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006812 NAS cation transport
GO:0007268 IEA synaptic transmission
GO:0007274 IEA neuromuscular synaptic transmission
GO:0007528 IEA neuromuscular junction development
GO:0007605 IMP sensory perception of sound
GO:0008144 IEA drug binding
GO:0008270 IEA zinc ion binding
GO:0009743 IEA response to carbohydrate
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0010524 NAS positive regulation of calcium ion transport into cytosol
GO:0014069 IEA postsynaptic density
GO:0014832 IEA urinary bladder smooth muscle contraction
GO:0015276 TAS ligand-gated ion channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016151 IEA nickel cation binding
GO:0016324 IDA apical plasma membrane
GO:0019228 IEA neuronal action potential
GO:0030432 IEA peristalsis
GO:0033198 IEA response to ATP
GO:0034220 TAS ion transmembrane transport
GO:0035091 IEA phosphatidylinositol binding
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0042734 IEA presynaptic membrane
GO:0042802 IPI identical protein binding
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0043235 IDA receptor complex
GO:0045340 IEA mercury ion binding
GO:0046870 IEA cadmium ion binding
GO:0048266 IEA behavioral response to pain
GO:0048741 IEA skeletal muscle fiber development
GO:0050850 NAS positive regulation of calcium-mediated signaling
GO:0050897 IEA cobalt ion binding
GO:0050909 IEA sensory perception of taste
GO:0051260 IPI protein homooligomerization
GO:0051291 IEA protein heterooligomerization
GO:0098655 NAS cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002300 p2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 protein_coding Danio_rerio
ENSMUSG00000029503 P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 protein_coding Mus_musculus

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