C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zona pellucida glycoprotein 3 (sperm receptor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188372 ZP3 9606 + 7:76397518-76442071 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336517 ZP3-002 76397518-76442071 protein_coding
  ENST00000394857 ZP3-001 76424907-76442071 protein_coding
  ENST00000394860 ZP3-008 76433470-76442063 protein_coding
  ENST00000416245 ZP3-003 76428638-76442062 protein_coding
  ENST00000466960 ZP3-004 76433956-76442071 retained_intron
  ENST00000467555 ZP3-005 76439898-76442071 processed_transcript
  ENST00000479793 ZP3-007 76434035-76442071 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336517ENST00000394857ENST00000394860ENST00000416245ENST00000467555
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336517 0.488±0.00 0.717±0.00 0.207±0.00 1.419±0.00 0.693±0.00 N/A 0.641±0.00 N/A 0.056±0.00 N/A 1.155±0.75 0.485±0.15 0.297±0.00
ENST00000394857 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.969±0.00 0.618±0.00
ENST00000394860 N/A N/A N/A N/A 0.204±0.00 N/A N/A 0.089±0.00 N/A N/A N/A N/A N/A
ENST00000416245 N/A 0.630±0.00 0.466±0.00 N/A 0.180±0.00 0.032±0.00 N/A N/A 0.151±0.00 N/A N/A N/A 0.452±0.00
ENST00000467555 1.690±0.00 2.667±0.00 0.547±0.00 9.780±0.00 N/A N/A N/A N/A N/A 0.467±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006E6 CIL_0006E6_0001 CGP 7:76326794-76409695
CIL_0006E7 CIL_0006E7_0001 CGP 7:76389334-76442071
CIL_0006E4 CIL_0006E4_0001 CGP 7:76397518-76505995

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001669 ISS acrosomal vesicle
GO:0001809 ISS positive regulation of type IV hypersensitivity
GO:0001825 ISS blastocyst formation
GO:0002081 ISS outer acrosomal membrane
GO:0002455 ISS humoral immune response mediated by circulating immunoglobulin
GO:0002687 ISS positive regulation of leukocyte migration
GO:0002922 IDA positive regulation of humoral immune response
GO:0004871 IMP signal transducer activity
GO:0005384 ISS manganese ion transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005576 IEA:TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IMP extracellular space
GO:0005737 IDA cytoplasm
GO:0005771 ISS multivesicular body
GO:0005783 ISS endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0006828 ISS manganese ion transport
GO:0006886 ISS intracellular protein transport
GO:0007338 TAS single fertilization
GO:0007339 IMP binding of sperm to zona pellucida
GO:0010513 ISS positive regulation of phosphatidylinositol biosynthetic process
GO:0015279 IDA store-operated calcium channel activity
GO:0016021 IEA integral component of membrane
GO:0030141 ISS secretory granule
GO:0030246 IDA carbohydrate binding
GO:0031012 IDA extracellular matrix
GO:0032190 IPI acrosin binding
GO:0032504 TAS multicellular organism reproduction
GO:0032729 ISS positive regulation of interferon-gamma production
GO:0032753 ISS positive regulation of interleukin-4 production
GO:0035556 IMP intracellular signal transduction
GO:0035803 ISS egg coat formation
GO:0042102 ISS positive regulation of T cell proliferation
GO:0045860 IDA positive regulation of protein kinase activity
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048015 ISS phosphatidylinositol-mediated signaling
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048599 ISS oocyte development
GO:0050729 ISS positive regulation of inflammatory response
GO:0051897 ISS positive regulation of protein kinase B signaling
GO:0070528 IMP protein kinase C signaling
GO:0070588 IDA calcium ion transmembrane transport
GO:0071421 ISS manganese ion transmembrane transport
GO:0090280 IDA positive regulation of calcium ion import
GO:2000344 IDA positive regulation of acrosome reaction
GO:2000360 IDA negative regulation of binding of sperm to zona pellucida
GO:2000368 IMP positive regulation of acrosomal vesicle exocytosis
GO:2000386 ISS positive regulation of ovarian follicle development
GO:2000388 ISS positive regulation of antral ovarian follicle growth

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016908 zgc:171779 zgc:171779 protein_coding Danio_rerio
ENSDARG00000039828 zp3b zona pellucida glycoprotein 3b protein_coding Danio_rerio
ENSDARG00000042129 zp3a.1 zona pellucida glycoprotein 3a, tandem duplicate 1 protein_coding Danio_rerio
ENSDARG00000042130 zp3a.2 zona pellucida glycoprotein 3a, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000087209 zp3.2 zona pellucida glycoprotein 3, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000089352 zp3.2 zona pellucida glycoprotein 3, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000089690 CABZ01044980.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000090768 zgc:173556 zgc:173556 protein_coding Danio_rerio
ENSMUSG00000004948 Zp3 zona pellucida glycoprotein 3 protein_coding Mus_musculus

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