C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: indoleamine 2,3-dioxygenase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188676 IDO2 9606 + 8:39934614-40016391 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343295 IDO2-001 39934614-40016391 processed_transcript
  ENST00000389060 IDO2-004 39949166-40015605 protein_coding
  ENST00000418094 IDO2-003 39987743-40016391 processed_transcript
  ENST00000502986 IDO2-201 39934955-40016391 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343295ENST00000389060ENST00000418094ENST00000502986
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343295 0.058±0.00 0.249±0.00 N/A 0.079±0.00 0.079±0.00 0.045±0.00 0.024±0.01 0.097±0.00 0.023±0.00 0.131±0.00 0.025±0.00 0.033±0.01 0.463±0.00 0.118±0.02
ENST00000389060 N/A N/A 0.053±0.00 N/A N/A 0.276±0.00 N/A N/A 0.100±0.00 N/A N/A 0.066±0.00 N/A N/A
ENST00000418094 N/A N/A N/A N/A N/A N/A N/A N/A 0.075±0.00 N/A N/A 0.020±0.00 2.067±1.50 0.306±0.00
ENST00000502986 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.565±0.35 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004833 EXP tryptophan 2,3-dioxygenase activity
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0006569 TAS tryptophan catabolic process
GO:0019441 IEA tryptophan catabolic process to kynurenine
GO:0020037 IEA heme binding
GO:0033754 ISS indoleamine 2,3-dioxygenase activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033594 ido1 indoleamine 2,3-dioxygenase 1 protein_coding Danio_rerio
ENSMUSG00000031549 Ido2 indoleamine 2,3-dioxygenase 2 protein_coding Mus_musculus

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