C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lon peptidase 1, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196365 LONP1 9606 - 19:5691834-5720572 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360614 LONP1-001 5691834-5720290 protein_coding
  ENST00000540670 LONP1-002 5691835-5720572 protein_coding
  ENST00000585374 LONP1-003 5691835-5720146 protein_coding
  ENST00000586617 LONP1-009 5707812-5720146 nonsense_mediated_decay
  ENST00000587365 LONP1-015 5700909-5720143 protein_coding
  ENST00000587552 LONP1-008 5691834-5719804 retained_intron
  ENST00000588589 LONP1-013 5700885-5708032 retained_intron
  ENST00000589473 LONP1-016 5691993-5694546 protein_coding
  ENST00000590206 LONP1-014 5696687-5707811 protein_coding
  ENST00000590511 LONP1-010 5717355-5720163 processed_transcript
  ENST00000590558 LONP1-017 5691835-5719871 nonsense_mediated_decay
  ENST00000590728 LONP1-011 5714903-5720156 processed_transcript
  ENST00000590729 LONP1-007 5691955-5719849 protein_coding
  ENST00000591321 LONP1-012 5705911-5708958 retained_intron
  ENST00000593119 LONP1-005 5691835-5720165 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360614ENST00000585374ENST00000590729ENST00000593119
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360614 21.739±0.00 N/A N/A 24.789±0.00 N/A N/A 4.912±0.00 16.974±0.00 N/A N/A N/A N/A N/A
ENST00000585374 N/A 2.422±0.00 6.257±0.00 N/A 3.278±0.00 7.379±4.78 N/A 22.619±0.00 2.546±0.00 16.733±11.94 11.593±8.17 35.831±6.86 19.395±0.00
ENST00000590729 24.896±0.00 N/A 22.877±0.00 N/A N/A 18.830±0.00 N/A N/A N/A N/A 14.655±0.00 22.272±0.00 16.416±0.00
ENST00000593119 N/A 1.458±0.00 18.248±0.00 N/A N/A N/A N/A 3.684±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005C5 CIL_0005C5_0001 CGP 19:5691834-5778734

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000002 NAS mitochondrial genome maintenance
GO:0001666 IEP response to hypoxia
GO:0003697 IEA single-stranded DNA binding
GO:0003727 IDA single-stranded RNA binding
GO:0004176 IEA:IDA ATP-dependent peptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 IEA:IMP mitochondrial matrix
GO:0006200 IEA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006508 IEA proteolysis
GO:0006515 IEA misfolded or incompletely synthesized protein catabolic process
GO:0007005 IMP mitochondrion organization
GO:0007568 IEA aging
GO:0009378 IEA four-way junction helicase activity
GO:0009725 IEA response to hormone
GO:0010044 IEA response to aluminum ion
GO:0016020 IDA membrane
GO:0016887 IEA ATPase activity
GO:0030163 IEA protein catabolic process
GO:0032042 NAS mitochondrial DNA metabolic process
GO:0034599 IEA:IC cellular response to oxidative stress
GO:0042645 IDA mitochondrial nucleoid
GO:0043531 IDA ADP binding
GO:0043565 IEA:IDA sequence-specific DNA binding
GO:0043623 IEA cellular protein complex assembly
GO:0051131 IEA chaperone-mediated protein complex assembly
GO:0051260 IDA protein homooligomerization
GO:0051603 IDA proteolysis involved in cellular protein catabolic process
GO:0051880 IDA G-quadruplex DNA binding
GO:0070182 IPI DNA polymerase binding
GO:0070361 IDA mitochondrial light strand promoter anti-sense binding
GO:0070362 IDA mitochondrial heavy strand promoter anti-sense binding
GO:0070407 IEA:IMP oxidation-dependent protein catabolic process
GO:0090296 IEA regulation of mitochondrial DNA replication

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071674 lonp1 lon peptidase 1, mitochondrial protein_coding Danio_rerio
ENSMUSG00000041168 Lonp1 lon peptidase 1, mitochondrial protein_coding Mus_musculus

Loading