C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPH receptor B4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196411 EPHB4 9606 - 7:100802565-100827521 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358173 EPHB4-001 100802565-100827499 protein_coding
  ENST00000360620 EPHB4-005 100802565-100827115 protein_coding
  ENST00000467515 EPHB4-008 100807365-100813339 retained_intron
  ENST00000477446 EPHB4-004 100813989-100827030 processed_transcript
  ENST00000478459 EPHB4-007 100806418-100814088 retained_intron
  ENST00000487222 EPHB4-002 100802568-100825526 retained_intron
  ENST00000489808 EPHB4-003 100817245-100827030 processed_transcript
  ENST00000492403 EPHB4-009 100805973-100807579 retained_intron
  ENST00000492878 EPHB4-006 100818551-100820482 retained_intron
  ENST00000616502 EPHB4-201 100802565-100827521 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358173ENST00000360620ENST00000467515ENST00000478459ENST00000489808ENST00000616502
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358173 23.083±0.00 16.535±0.00 0.983±0.00 N/A 6.796±2.65 4.977±3.02 7.463±6.49 10.731±0.00 15.593±0.00 6.525±4.47 N/A 32.137±20.31 36.147±14.15 13.764±0.00
ENST00000360620 N/A 11.904±0.00 N/A N/A 4.839±0.00 N/A N/A N/A N/A N/A 1.414±0.00 28.880±0.00 11.456±3.58 7.242±0.00
ENST00000467515 N/A N/A N/A N/A N/A N/A 1.445±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000478459 N/A N/A 3.424±0.00 0.932±0.00 8.021±0.00 4.001±0.00 1.627±0.00 10.003±0.00 7.861±0.00 6.239±0.00 N/A 47.793±28.40 68.418±0.00 8.605±0.00
ENST00000489808 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.647±0.00 N/A N/A N/A
ENST00000616502 N/A N/A N/A N/A N/A 3.252±0.00 N/A 1.238±0.00 2.292±0.00 N/A 0.193±0.00 18.833±0.00 N/A 6.612±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 ISS angiogenesis
GO:0002042 IDA cell migration involved in sprouting angiogenesis
GO:0003007 ISS heart morphogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IDA transmembrane receptor protein tyrosine kinase activity
GO:0005003 IDA:IEA ephrin receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IDA:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007155 IDA cell adhesion
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0046777 IDA protein autophosphorylation
GO:0048013 IDA:IEA ephrin receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027112 ephb4b eph receptor B4b protein_coding Danio_rerio
ENSDARG00000040346 ephb4a eph receptor B4a protein_coding Danio_rerio
ENSMUSG00000029710 Ephb4 Eph receptor B4 protein_coding Mus_musculus

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