C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor 2 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197081 IGF2R 9606 + 6:159969099-160113507 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356956 IGF2R-001 159969099-160106551 protein_coding
  ENST00000464636 IGF2R-002 160010338-160024693 retained_intron
  ENST00000475584 IGF2R-006 160096447-160113507 processed_transcript
  ENST00000475834 IGF2R-005 160085061-160090340 protein_coding
  ENST00000487607 IGF2R-004 160073416-160074061 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356956
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356956 30.650±0.00 12.839±0.00 6.543±0.00 2.948±1.58 10.188±5.12 14.684±0.00 11.726±8.61 11.040±7.33 9.250±5.26 8.725±1.85 31.202±19.66 23.180±11.25 12.033±1.65 9.936±2.74

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089P CIL_00089P_0001 VISTA 6:159654795-160257694
CIL_0002QF CIL_0002QF_0002 CGP 6:159969099-160158718

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0001948 IDA glycoprotein binding
GO:0001965 IEA G-protein alpha-subunit binding
GO:0001972 IEA retinoic acid binding
GO:0004872 TAS receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005010 TAS insulin-like growth factor-activated receptor activity
GO:0005215 IEA transporter activity
GO:0005515 IPI protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005537 IEA mannose binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005641 IEA nuclear envelope lumen
GO:0005737 IEA cytoplasm
GO:0005764 IEA lysosome
GO:0005768 IDA endosome
GO:0005770 IDA late endosome
GO:0005802 IEA trans-Golgi network
GO:0005886 IEA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005925 IDA focal adhesion
GO:0006810 IEA transport
GO:0006898 TAS receptor-mediated endocytosis
GO:0007165 TAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007283 IEA spermatogenesis
GO:0009791 IEA post-embryonic development
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019899 IEA enzyme binding
GO:0030118 IEA clathrin coat
GO:0030139 IDA endocytic vesicle
GO:0030140 IDA trans-Golgi network transport vesicle
GO:0031100 IEA organ regeneration
GO:0031995 IEA insulin-like growth factor II binding
GO:0032526 IEA response to retinoic acid
GO:0042802 IPI identical protein binding
GO:0042981 IEA regulation of apoptotic process
GO:0043065 IEA positive regulation of apoptotic process
GO:0048009 TAS insulin-like growth factor receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051219 IDA phosphoprotein binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006094 igf2r insulin-like growth factor 2 receptor protein_coding Danio_rerio
ENSMUSG00000023830 Igf2r insulin-like growth factor 2 receptor protein_coding Mus_musculus

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