C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 2, subfamily B, polypeptide 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197408 CYP2B6 9606 + 19:40991299-41018398 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324071 CYP2B6-001 40991299-41018398 protein_coding
  ENST00000593831 CYP2B6-002 41003946-41017373 protein_coding
  ENST00000594187 CYP2B6-005 41004379-41007175 retained_intron
  ENST00000597612 CYP2B6-003 41009677-41017847 retained_intron
  ENST00000598834 CYP2B6-004 40991404-41007531 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324071ENST00000593831ENST00000594187ENST00000597612ENST00000598834
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324071 N/A N/A 0.650±0.00 N/A N/A N/A 0.023±0.00 30.576±0.00 133.127±0.00 N/A N/A 0.099±0.09 N/A 0.074±0.00
ENST00000593831 0.022±0.00 0.189±0.00 0.766±0.00 0.030±0.00 0.172±0.07 1.386±0.00 0.036±0.01 N/A N/A N/A 0.110±0.00 N/A 0.074±0.00 0.122±0.00
ENST00000594187 N/A N/A N/A N/A 0.929±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.142±0.00
ENST00000597612 0.035±0.00 N/A N/A 0.110±0.00 N/A 0.075±0.00 N/A 0.531±0.00 N/A 0.029±0.00 N/A 0.147±0.00 N/A 0.032±0.00
ENST00000598834 0.135±0.00 N/A N/A 0.093±0.00 0.310±0.00 N/A N/A N/A 0.148±0.00 N/A N/A 0.321±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007H6 CIL_0007H6_0008 CGP 19:40875439-41018398
CIL_0007H6 CIL_0007H6_0005 CGP 19:40991299-41096195

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006805 IDA xenobiotic metabolic process
GO:0008202 IMP steroid metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0017144 IMP drug metabolic process
GO:0020037 IDA:IEA heme binding
GO:0042180 IDA cellular ketone metabolic process
GO:0042738 IDA exogenous drug catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IDA:IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007173 cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 protein_coding Danio_rerio
ENSDARG00000068493 si:zfos-411a11.2 si:zfos-411a11.2 protein_coding Danio_rerio
ENSMUSG00000030483 Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 protein_coding Mus_musculus
ENSMUSG00000040583 Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 protein_coding Mus_musculus
ENSMUSG00000040650 Cyp2b23 cytochrome P450, family 2, subfamily b, polypeptide 23 protein_coding Mus_musculus
ENSMUSG00000040660 Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 protein_coding Mus_musculus
ENSMUSG00000066704 Cyp2b19 cytochrome P450, family 2, subfamily b, polypeptide 19 protein_coding Mus_musculus

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