C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: elastase, neutrophil expressed
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197561 ELANE 9606 + 19:851014-856247 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263621 ELANE-201 852291-856242 protein_coding
  ENST00000590230 ELANE-001 851014-856247 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263621ENST00000590230
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263621 34.951±0.00 0.480±0.00 0.277±0.19 0.916±0.00 0.495±0.00 N/A N/A 0.852±0.00 49.734±0.00 0.087±0.00 0.412±0.00 0.869±0.96 0.471±0.00
ENST00000590230 N/A N/A N/A N/A 0.984±0.00 0.634±0.00 0.415±0.00 N/A N/A N/A 1.086±0.00 N/A 0.948±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0000HZ CIL_0000HZ_0001 CGP 19:840960-856247
CIL_000316 CIL_000316_0001 CGP 19:851014-863630

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IMP RNA polymerase II transcription corepressor activity
GO:0001878 IEA response to yeast
GO:0002020 IPI protease binding
GO:0002438 IEA acute inflammatory response to antigenic stimulus
GO:0003824 IEA catalytic activity
GO:0004175 IDA endopeptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005737 IDA cytoplasm
GO:0006508 IDA:IEA proteolysis
GO:0006874 NAS cellular calcium ion homeostasis
GO:0006909 IEA phagocytosis
GO:0008201 IDA heparin binding
GO:0008233 IDA peptidase activity
GO:0009411 IDA response to UV
GO:0009986 IDA cell surface
GO:0017053 IDA transcriptional repressor complex
GO:0019955 IPI cytokine binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030141 IDA secretory granule
GO:0030163 NAS protein catabolic process
GO:0030198 TAS extracellular matrix organization
GO:0030574 TAS collagen catabolic process
GO:0032496 IEA response to lipopolysaccharide
GO:0042742 IDA defense response to bacterium
GO:0043406 NAS positive regulation of MAP kinase activity
GO:0044130 IEA negative regulation of growth of symbiont in host
GO:0045079 IDA negative regulation of chemokine biosynthetic process
GO:0045415 IDA negative regulation of interleukin-8 biosynthetic process
GO:0045416 IDA positive regulation of interleukin-8 biosynthetic process
GO:0048661 IDA positive regulation of smooth muscle cell proliferation
GO:0050728 NAS negative regulation of inflammatory response
GO:0050778 IEA positive regulation of immune response
GO:0050832 IEA defense response to fungus
GO:0050900 IEA leukocyte migration
GO:0050922 NAS negative regulation of chemotaxis
GO:0070062 IDA extracellular vesicular exosome
GO:0070947 IEA neutrophil mediated killing of fungus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000020125 Elane elastase, neutrophil expressed protein_coding Mus_musculus

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