C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium large conductance calcium-activated channel, subfamily M, beta member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197584 KCNMB2 9606 + 3:178272932-178844429 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358316 KCNMB2-201 178807338-178844428 protein_coding
  ENST00000420517 KCNMB2-004 178536205-178843141 protein_coding
  ENST00000422927 KCNMB2-013 178558885-178828266 nonsense_mediated_decay
  ENST00000432997 KCNMB2-003 178558700-178844429 protein_coding
  ENST00000436247 KCNMB2-014 178807339-178820711 processed_transcript
  ENST00000437510 KCNMB2-002 178272932-178828362 protein_coding
  ENST00000452583 KCNMB2-001 178536236-178843141 protein_coding
  ENST00000455865 KCNMB2-012 178558830-178828250 protein_coding
  ENST00000470361 KCNMB2-011 178536236-178824680 processed_transcript
  ENST00000617329 KCNMB2-202 178807338-178844428 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358316ENST00000422927ENST00000432997ENST00000437510ENST00000452583ENST00000470361ENST00000617329
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358316 N/A N/A N/A 0.150±0.00 0.163±0.03 0.928±0.00 N/A 0.341±0.00 N/A 0.918±0.00 0.064±0.00 N/A
ENST00000422927 N/A N/A 0.094±0.00 N/A N/A N/A 0.054±0.00 N/A N/A N/A N/A N/A
ENST00000432997 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.053±0.67 N/A N/A
ENST00000437510 N/A N/A N/A N/A 0.783±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000452583 N/A 0.425±0.00 N/A N/A 0.305±0.00 N/A 0.098±0.00 0.458±0.00 N/A 1.291±0.40 0.026±0.00 N/A
ENST00000470361 0.058±0.00 N/A N/A 0.144±0.00 N/A N/A N/A N/A 0.035±0.00 0.818±0.00 N/A N/A
ENST00000617329 N/A N/A 0.063±0.03 0.117±0.09 N/A N/A 0.003±0.00 N/A N/A 0.203±0.17 0.061±0.00 0.316±0.28

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001508 IDA action potential
GO:0005513 IDA detection of calcium ion
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006813 IDA:IEA potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0008076 IDA voltage-gated potassium channel complex
GO:0008200 TAS ion channel inhibitor activity
GO:0015269 IEA:IDA calcium-activated potassium channel activity
GO:0015459 TAS potassium channel regulator activity
GO:0016020 IEA membrane
GO:0019228 IDA neuronal action potential
GO:0019229 TAS regulation of vasoconstriction
GO:0071805 IEA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001712 CR855338.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000006568 kcnmb2 potassium large conductance calcium-activated channel, subfamily M, beta member 2 protein_coding Danio_rerio
ENSMUSG00000037610 Kcnmb2 potassium large conductance calcium-activated channel, subfamily M, beta member 2 protein_coding Mus_musculus

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