C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement factor D (adipsin)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197766 CFD 9606 + 19:859643-863630 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327726 CFD-001 859643-863630 protein_coding
  ENST00000592860 CFD-002 859664-863238 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000327726ENST00000592860
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000327726 110.096±0.00 32.804±0.00 0.274±0.00 0.630±0.19 129.857±98.98 86.483±75.86 50.163±39.92 3.883±1.63 19.563±15.75 140.384±129.11 30.250±0.10 15.739±13.60 35.926±11.11 39.152±30.06
ENST00000592860 478.852±0.00 112.759±0.00 N/A 0.353±0.00 1203.110±0.00 661.543±0.00 116.088±0.00 13.029±0.00 3.970±0.00 522.378±0.00 47.648±0.00 10.055±1.25 59.658±15.83 154.046±112.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_000316 CIL_000316_0001 CGP 19:851014-863630
CIL_0000HX CIL_0000HX_0001 CGP 19:859643-893218

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0006508 IEA proteolysis
GO:0006956 TAS complement activation
GO:0006957 TAS complement activation, alternative pathway
GO:0007596 TAS blood coagulation
GO:0008236 TAS serine-type peptidase activity
GO:0030168 TAS platelet activation
GO:0031093 TAS platelet alpha granule lumen
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039579 cfd complement factor D (adipsin) protein_coding Danio_rerio
ENSMUSG00000061780 Cfd complement factor D (adipsin) protein_coding Mus_musculus

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