C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mesoderm induction early response 1, transcriptional regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198160 MIER1 9606 + 1:66924895-66988619 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355356 MIER1-002 66930243-66988030 protein_coding
  ENST00000355977 MIER1-201 66924895-66988619 protein_coding
  ENST00000357692 MIER1-001 66924957-66988031 protein_coding
  ENST00000371012 MIER1-003 66924967-66948240 protein_coding
  ENST00000371014 MIER1-008 66924959-66986670 protein_coding
  ENST00000371016 MIER1-006 66924959-66986670 protein_coding
  ENST00000371018 MIER1-202 66924895-66988619 protein_coding
  ENST00000401041 MIER1-009 66924959-66985684 protein_coding
  ENST00000401042 MIER1-007 66930243-66986670 protein_coding
  ENST00000479067 MIER1-004 66932652-66959750 processed_transcript
  ENST00000493357 MIER1-005 66958911-66960078 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355356ENST00000355977ENST00000357692ENST00000371014ENST00000371018ENST00000401041ENST00000401042ENST00000479067
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355356 8.676±0.00 7.559±0.00 0.997±0.00 3.778±2.08 3.844±2.78 9.674±1.15 1.455±1.11 7.457±0.00 3.673±1.53 7.193±2.69 2.070±1.98 4.477±2.39 3.828±1.54 9.985±0.00
ENST00000355977 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.145±0.00 N/A N/A
ENST00000357692 N/A N/A N/A 1.313±0.00 N/A N/A N/A 2.855±0.00 N/A 1.776±0.00 N/A 0.590±0.00 0.405±0.00 3.656±0.95
ENST00000371014 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.215±0.00 N/A 6.166±0.00
ENST00000371018 N/A N/A 1.042±0.00 N/A N/A N/A N/A N/A N/A N/A 0.087±0.00 N/A N/A N/A
ENST00000401041 N/A N/A 1.790±0.00 2.179±0.00 2.817±0.00 4.794±0.00 0.530±0.00 N/A 3.004±0.00 4.083±0.00 N/A 3.442±0.00 N/A N/A
ENST00000401042 N/A N/A N/A N/A 2.782±0.00 N/A 1.140±0.00 1.713±0.00 3.464±0.00 N/A N/A 2.913±0.60 9.491±0.00 16.775±0.00
ENST00000479067 N/A N/A 5.353±0.00 5.877±0.00 5.638±0.00 N/A 2.076±0.00 N/A 8.946±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000261 CIL_000261_0001 CGP 1:66812885-66988619
CIL_00069G CIL_00069G_0001 CGP 1:66924895-67054099

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0004871 IMP signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007165 IMP signal transduction
GO:0017053 IDA transcriptional repressor complex
GO:0031937 IDA positive regulation of chromatin silencing
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001447 mier1b mesoderm induction early response 1b protein_coding Danio_rerio
ENSDARG00000041072 mier1a mesoderm induction early response 1 homolog a (Xenopus laevis) protein_coding Danio_rerio
ENSMUSG00000028522 Mier1 mesoderm induction early response 1 homolog (Xenopus laevis protein_coding Mus_musculus

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