C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: intersectin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198399 ITSN2 9606 - 2:24202864-24360714 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355123 ITSN2-001 24202864-24360714 protein_coding
  ENST00000361999 ITSN2-002 24202864-24360309 protein_coding
  ENST00000406921 ITSN2-004 24220319-24360508 protein_coding
  ENST00000407704 ITSN2-006 24311620-24360472 processed_transcript
  ENST00000412011 ITSN2-003 24286323-24360509 protein_coding
  ENST00000416160 ITSN2-008 24238933-24248699 protein_coding
  ENST00000427234 ITSN2-010 24203282-24209948 nonsense_mediated_decay
  ENST00000443927 ITSN2-012 24310344-24360490 protein_coding
  ENST00000449392 ITSN2-011 24204363-24208316 nonsense_mediated_decay
  ENST00000469848 ITSN2-007 24293261-24295711 retained_intron
  ENST00000478720 ITSN2-005 24202864-24205693 retained_intron
  ENST00000479575 ITSN2-009 24205266-24210329 retained_intron
  ENST00000622089 ITSN2-201 24202867-24328118 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355123ENST00000361999ENST00000416160ENST00000622089
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355123 N/A N/A N/A N/A N/A N/A 0.365±0.00 N/A N/A 1.591±0.00 N/A N/A N/A N/A
ENST00000361999 1.841±0.00 2.369±0.00 N/A 1.060±0.00 3.479±0.00 N/A N/A N/A N/A N/A N/A 2.871±0.28 1.656±0.00 4.511±0.00
ENST00000416160 3.168±0.00 5.065±0.00 1.349±0.00 0.979±0.00 1.722±0.00 2.149±0.50 N/A 3.998±0.00 1.134±0.00 4.199±0.37 2.208±0.00 2.525±0.37 1.730±0.39 3.761±0.00
ENST00000622089 1.699±0.00 N/A N/A 1.148±0.00 1.312±0.00 2.711±0.23 1.313±0.88 2.769±1.97 1.560±0.12 3.665±0.82 2.986±0.00 1.824±0.70 2.300±0.59 3.740±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000024 CIL_000024_0002 CGP 2:24175069-24360714

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0006897 IEA endocytosis
GO:0009967 TAS positive regulation of signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000161 itsn2a intersectin 2a protein_coding Danio_rerio
ENSDARG00000054973 itsn2b intersectin 2b protein_coding Danio_rerio
ENSMUSG00000020640 Itsn2 intersectin 2 protein_coding Mus_musculus

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