C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: meningioma expressed antigen 5 (hyaluronidase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198408 MGEA5 9606 - 10:101784443-101818465 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357797 MGEA5-004 101786134-101818418 protein_coding
  ENST00000361464 MGEA5-003 101784443-101818418 protein_coding
  ENST00000370094 MGEA5-005 101797046-101818418 protein_coding
  ENST00000429860 MGEA5-002 101803747-101817866 protein_coding
  ENST00000439817 MGEA5-201 101784443-101818465 protein_coding
  ENST00000461645 MGEA5-010 101786563-101791453 processed_transcript
  ENST00000462994 MGEA5-011 101786102-101787965 processed_transcript
  ENST00000479811 MGEA5-008 101786534-101798017 processed_transcript
  ENST00000482611 MGEA5-006 101786134-101799332 processed_transcript
  ENST00000492204 MGEA5-009 101792608-101794095 processed_transcript
  ENST00000494347 MGEA5-001 101786144-101792946 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361464ENST00000370094ENST00000439817ENST00000482611
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361464 21.774±0.00 12.718±0.00 1.757±0.00 15.674±8.20 22.200±9.19 13.987±5.01 9.486±7.19 7.899±3.35 3.917±2.17 6.242±0.00 7.614±0.00 9.456±5.25 8.134±0.99 17.989±3.35
ENST00000370094 N/A N/A 6.380±0.00 N/A N/A N/A 1.989±0.00 2.231±0.00 3.601±0.00 6.063±0.00 N/A N/A N/A N/A
ENST00000439817 4.122±0.00 N/A N/A 6.757±0.00 N/A N/A N/A N/A N/A N/A N/A 2.776±0.00 N/A 7.561±0.00
ENST00000482611 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.204±0.00 N/A 11.891±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089J CIL_00089J_0001 VISTA 10:101185253-101786853
CIL_000942 CIL_000942_0001 VISTA 10:101206892-101808215
CIL_00099F CIL_00099F_0001 VISTA 10:101467436-102068636
CIL_00099E CIL_00099E_0001 VISTA 10:101480423-102081273
CIL_0005NB CIL_0005NB_0001 CGP 10:101781325-101818465
CIL_0005NM CIL_0005NM_0001 CGP 10:101784443-101843920

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004402 IEA histone acetyltransferase activity
GO:0004415 TAS hyalurononglucosaminidase activity
GO:0005634 IEA nucleus
GO:0005829 IDA cytosol
GO:0006044 IDA N-acetylglucosamine metabolic process
GO:0006516 TAS glycoprotein catabolic process
GO:0006517 IDA protein deglycosylation
GO:0006612 IEA protein targeting to membrane
GO:0007568 IEA aging
GO:0010524 IEA positive regulation of calcium ion transport into cytosol
GO:0010616 IEA negative regulation of cardiac muscle adaptation
GO:0016020 IDA membrane
GO:0016231 IDA beta-N-acetylglucosaminidase activity
GO:0031343 IEA positive regulation of cell killing
GO:0032024 IEA positive regulation of insulin secretion
GO:0043243 IEA positive regulation of protein complex disassembly
GO:0045862 IEA positive regulation of proteolysis
GO:0046060 IEA dATP metabolic process
GO:0046326 IEA positive regulation of glucose import
GO:0048545 IEA response to steroid hormone
GO:0051054 IEA positive regulation of DNA metabolic process
GO:0051901 IEA positive regulation of mitochondrial depolarization
GO:0051928 IEA positive regulation of calcium ion transport
GO:0060051 IEA negative regulation of protein glycosylation
GO:0060124 IEA positive regulation of growth hormone secretion
GO:0070265 IEA necrotic cell death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074686 mgea5 meningioma expressed antigen 5 (hyaluronidase) protein_coding Danio_rerio
ENSMUSG00000025220 Mgea5 meningioma expressed antigen 5 (hyaluronidase) protein_coding Mus_musculus

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