C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SMG5 nonsense mediated mRNA decay factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198952 SMG5 9606 - 1:156249224-156282825 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361813 SMG5-001 156249224-156282825 protein_coding
  ENST00000468993 SMG5-003 156253048-156253762 retained_intron
  ENST00000473643 SMG5-004 156251079-156252555 retained_intron
  ENST00000476954 SMG5-005 156250033-156251380 retained_intron
  ENST00000489907 SMG5-008 156266137-156267588 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361813
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361813 6.811±0.00 10.702±0.00 1.442±0.00 9.426±3.62 7.772±4.48 6.639±3.99 15.185±11.58 11.509±9.14 7.407±5.38 7.870±3.61 6.993±0.85 18.411±8.00 21.821±4.12 20.065±6.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000898 CIL_000898_0001 VISTA 1:155789635-156392759
CIL_0008P5 CIL_0008P5_0001 VISTA 1:155795688-156399252
CIL_0008JO CIL_0008JO_0001 VISTA 1:156202708-156805613

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006406 TAS mRNA export from nucleus
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0035303 IMP regulation of dephosphorylation
GO:0051721 IDA protein phosphatase 2A binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041481 smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) protein_coding Danio_rerio
ENSMUSG00000001415 Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) protein_coding Mus_musculus

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