C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000203747 FCGR3A 9606 - 1:161541759-161550737 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367967 FCGR3A-003 161541796-161550591 protein_coding
  ENST00000367969 FCGR3A-001 161541759-161550028 protein_coding
  ENST00000426740 FCGR3A-005 161541855-161549789 protein_coding
  ENST00000436743 FCGR3A-201 161541765-161550623 protein_coding
  ENST00000442336 FCGR3A-004 161548421-161550737 protein_coding
  ENST00000443193 FCGR3A-202 161541763-161550028 protein_coding
  ENST00000476031 FCGR3A-002 161545399-161549730 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367967ENST00000426740ENST00000436743ENST00000443193
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367967 9.389±0.00 11.264±0.00 0.545±0.00 N/A 3.635±0.00 N/A 1.143±0.47 3.147±0.00 N/A N/A N/A 2.622±1.14 19.301±8.46 3.907±0.00
ENST00000426740 4.362±0.00 N/A N/A 10.941±0.00 N/A 1.556±0.00 0.843±0.00 6.389±0.00 5.559±4.78 25.559±0.00 0.744±0.00 5.653±0.00 13.542±5.32 1.382±0.00
ENST00000436743 4.927±0.00 5.028±0.00 N/A 1.664±0.00 3.970±0.00 0.355±0.00 0.368±0.00 3.855±1.57 3.618±0.00 9.986±1.24 N/A 2.567±1.40 16.118±12.16 0.997±0.78
ENST00000443193 N/A N/A N/A N/A 0.763±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005I7 CIL_0005I7_0001 CGP 1:161541759-161678654

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 TAS immune response
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0019864 IEA IgG binding
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS innate immune response
GO:0050776 TAS regulation of immune response
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000059089 Fcgr4 Fc receptor, IgG, low affinity IV protein_coding Mus_musculus

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