C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatase and actin regulator 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204138 PHACTR4 9606 + 1:28369603-28500369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373836 PHACTR4-004 28438171-28500308 protein_coding
  ENST00000373839 PHACTR4-001 28369603-28500369 protein_coding
  ENST00000463428 PHACTR4-003 28369739-28467241 processed_transcript
  ENST00000493669 PHACTR4-002 28369744-28497156 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373836ENST00000373839ENST00000463428ENST00000493669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373836 0.609±0.00 N/A 0.876±0.00 0.579±0.00 N/A 0.971±0.11 0.977±0.00 2.073±0.00 N/A 1.425±0.00 0.790±0.64 1.264±0.48 0.496±0.02 1.260±0.00
ENST00000373839 3.108±0.00 6.765±0.00 0.448±0.00 1.398±0.73 2.350±0.82 1.613±0.48 0.583±0.46 2.588±1.69 3.743±0.00 1.695±1.18 2.791±0.00 6.744±4.67 4.714±3.48 6.337±1.92
ENST00000463428 N/A N/A N/A N/A N/A N/A N/A N/A 5.524±0.00 1.951±0.00 N/A 1.880±0.00 N/A N/A
ENST00000493669 N/A N/A 2.726±0.00 0.866±0.07 N/A N/A 0.341±0.00 3.113±0.00 0.977±0.00 1.924±0.00 0.348±0.00 N/A N/A 1.978±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001755 ISS neural crest cell migration
GO:0001843 ISS neural tube closure
GO:0003779 ISS actin binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0007266 ISS Rho protein signal transduction
GO:0008157 ISS protein phosphatase 1 binding
GO:0030027 ISS lamellipodium
GO:0030036 ISS actin cytoskeleton organization
GO:0043085 ISS positive regulation of catalytic activity
GO:0048484 ISS enteric nervous system development
GO:0051726 ISS regulation of cell cycle
GO:0061386 ISS closure of optic fissure
GO:0071862 ISS protein phosphatase type 1 activator activity
GO:2001045 ISS negative regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015552 phactr4a phosphatase and actin regulator 4a protein_coding Danio_rerio
ENSDARG00000032221 phactr4b phosphatase and actin regulator 4b protein_coding Danio_rerio
ENSMUSG00000066043 Phactr4 phosphatase and actin regulator 4 protein_coding Mus_musculus

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