C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock 70kDa protein 1A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204389 HSPA1A 9606 + 6:31815464-31817946 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375651 HSPA1A-001 31815464-31817946 protein_coding
  ENST00000608703 HSPA1A-002 31815543-31817946 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375651ENST00000608703
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375651 N/A N/A 4.884±0.00 6.305±0.00 27.603±0.00 9.596±0.00 4.774±0.00 N/A 10.022±0.00 N/A 12.733±0.00 0.889±0.00 N/A N/A
ENST00000608703 18.757±0.00 10.593±0.00 12.267±0.00 17.100±1.69 40.181±4.23 181.336±166.45 18.944±5.76 47.558±27.34 18.252±8.14 124.580±82.17 14.450±2.49 26.414±16.26 27.954±2.63 33.223±8.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PO CIL_0001PO_0004 CGP 6:31809619-31817946
CIL_0001PO CIL_0001PO_0003 CGP 6:31815464-31830255

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000902 IEA cell morphogenesis
GO:0001618 IEA virus receptor activity
GO:0001664 IPI G-protein coupled receptor binding
GO:0003725 IDA double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005783 TAS endoplasmic reticulum
GO:0005814 IDA centriole
GO:0005829 IDA cytosol
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006402 IDA mRNA catabolic process
GO:0006986 IDA response to unfolded protein
GO:0008180 IDA COP9 signalosome
GO:0008285 IMP negative regulation of cell proliferation
GO:0009615 IEA response to virus
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016234 IDA inclusion body
GO:0016235 IDA aggresome
GO:0016607 IDA nuclear speck
GO:0016887 IDA ATPase activity
GO:0019899 IPI enzyme binding
GO:0030308 IMP negative regulation of cell growth
GO:0030529 IDA ribonucleoprotein complex
GO:0031072 IPI heat shock protein binding
GO:0031397 IDA negative regulation of protein ubiquitination
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031982 IDA vesicle
GO:0034599 TAS cellular response to oxidative stress
GO:0034605 IDA cellular response to heat
GO:0042026 IDA protein refolding
GO:0042623 IDA ATPase activity, coupled
GO:0043066 TAS negative regulation of apoptotic process
GO:0044183 IDA protein binding involved in protein folding
GO:0044822 IDA poly(A) RNA binding
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0047485 IPI protein N-terminus binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050821 TAS protein stabilization
GO:0051082 NAS unfolded protein binding
GO:0060548 IDA negative regulation of cell death
GO:0070062 IDA extracellular vesicular exosome
GO:0070370 IMP cellular heat acclimation
GO:0072562 IDA blood microparticle
GO:0090084 IDA negative regulation of inclusion body assembly
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021924 hsp70.3 heat shock cognate 70-kd protein, tandem duplicate 3 protein_coding Danio_rerio
ENSDARG00000029688 mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) protein_coding Danio_rerio
ENSDARG00000055723 hsp70l heat shock cognate 70-kd protein, like protein_coding Danio_rerio
ENSDARG00000056210 si:ch211-199o1.2 si:ch211-199o1.2 protein_coding Danio_rerio
ENSDARG00000092362 hsp70.2 heat shock cognate 70-kd protein, tandem duplicate 2 protein_coding Danio_rerio
ENSMUSG00000090877 Hspa1b heat shock protein 1B protein_coding Mus_musculus
ENSMUSG00000091971 Hspa1a heat shock protein 1A protein_coding Mus_musculus

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