C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TBC1 domain family, member 8 (with GRAM domain)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204634 TBC1D8 9606 - 2:101007617-101252866 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376840 TBC1D8-011 101007617-101151253 protein_coding
  ENST00000409318 TBC1D8-001 101007617-101151384 protein_coding
  ENST00000462819 TBC1D8-006 101187824-101252855 processed_transcript
  ENST00000463469 TBC1D8-004 101090253-101252866 processed_transcript
  ENST00000473937 TBC1D8-007 101028303-101032944 retained_intron
  ENST00000481317 TBC1D8-008 101028467-101032481 processed_transcript
  ENST00000485851 TBC1D8-005 101187984-101252864 processed_transcript
  ENST00000485875 TBC1D8-009 101028345-101029972 retained_intron
  ENST00000487392 TBC1D8-003 101059452-101109963 processed_transcript
  ENST00000494011 TBC1D8-010 101011040-101022373 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376840ENST00000409318
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376840 4.490±0.00 5.079±0.00 2.052±0.00 1.897±0.00 3.534±1.01 2.792±0.50 5.004±2.96 5.666±3.25 4.110±2.16 8.375±2.96 4.556±1.70 7.741±3.85 1.712±0.00 9.970±0.12
ENST00000409318 1.992±0.00 N/A N/A 1.447±0.00 N/A N/A 2.343±1.16 N/A N/A N/A 3.867±1.65 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TG CIL_0008TG_0001 VISTA 2:100809636-101413030
CIL_0004HI CIL_0004HI_0001 CGP 2:100820152-101024032
CIL_0004HF CIL_0004HF_0001 CGP 2:101001715-101252866
CIL_0004HG CIL_0004HG_0001 CGP 2:101007617-101270316

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005097 IEA Rab GTPase activator activity
GO:0005509 IEA calcium ion binding
GO:0008015 TAS blood circulation
GO:0008284 TAS positive regulation of cell proliferation
GO:0016020 TAS membrane
GO:0032313 IEA regulation of Rab GTPase activity
GO:0032851 IEA positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000003134 Tbc1d8 TBC1 domain family, member 8 protein_coding Mus_musculus

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