C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: epithelial membrane protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213853 EMP2 9606 - 16:10528422-10580698 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342147 EMP2-002 10544180-10580632 retained_intron
  ENST00000359543 EMP2-001 10528422-10580698 protein_coding
  ENST00000536829 EMP2-003 10532849-10559154 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000359543ENST00000536829
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000359543 39.604±0.00 6.082±0.00 1.036±0.00 0.700±0.23 1.625±0.00 17.865±12.75 9.880±7.19 4.265±2.61 9.725±4.42 41.459±1.34 2.920±1.89 12.942±8.58 8.285±1.74 7.714±5.17
ENST00000536829 N/A N/A N/A N/A N/A N/A N/A N/A 56.545±0.00 170.418±0.00 8.676±0.00 N/A 18.268±1.38 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074W CIL_00074W_0001 CGP 16:10326434-10580698
CIL_00074X CIL_00074X_0001 CGP 16:10528422-10694945

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001954 IDA positive regulation of cell-matrix adhesion
GO:0003093 IDA regulation of glomerular filtration
GO:0005178 IPI integrin binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0008283 TAS cell proliferation
GO:0008284 IMP positive regulation of cell proliferation
GO:0010594 IDA regulation of endothelial cell migration
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0045765 IDA regulation of angiogenesis
GO:2001046 IDA positive regulation of integrin-mediated signaling pathway
GO:2001212 IDA regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044588 emp2 epithelial membrane protein 2 protein_coding Danio_rerio
ENSMUSG00000022505 Emp2 epithelial membrane protein 2 protein_coding Mus_musculus

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