C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DP beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000215048 HLA-DPB1 9606 + CHR_HSCHR6_MHC_QBL_CTG1:33004965-33016242 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000399491 HLA-DPB1-003 33005011-33016242 protein_coding
  ENST00000399500 HLA-DPB1-001 33004965-33016242 protein_coding
  ENST00000402095 HLA-DPB1-008 33009532-33014930 protein_coding
  ENST00000432661 HLA-DPB1-002 33009717-33016242 protein_coding
  ENST00000468854 HLA-DPB1-009 33009986-33012935 processed_transcript
  ENST00000469961 HLA-DPB1-006 33009431-33013057 processed_transcript
  ENST00000475215 HLA-DPB1-007 33009488-33014272 processed_transcript
  ENST00000486122 HLA-DPB1-004 33005049-33010277 retained_intron
  ENST00000494369 HLA-DPB1-005 33009431-33013998 processed_transcript

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 IMP cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032588 TAS trans-Golgi network membrane
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042605 IDA peptide antigen binding
GO:0042613 IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

No Homologs available.

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