C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DM beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000226264 HLA-DMB 9606 - CHR_HSCHR6_MHC_DBB_CTG1:32912565-32931062 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000437583 HLA-DMB-007 32912565-32915375 protein_coding
  ENST00000440078 HLA-DMB-001 32912565-32919006 protein_coding
  ENST00000447454 HLA-DMB-002 32912565-32918957 protein_coding
  ENST00000448798 HLA-DMB-006 32912565-32916624 protein_coding
  ENST00000449679 HLA-DMB-008 32915300-32931062 protein_coding
  ENST00000461570 HLA-DMB-003 32912565-32918920 retained_intron
  ENST00000477825 HLA-DMB-005 32912565-32914822 retained_intron
  ENST00000494382 HLA-DMB-004 32912565-32914837 retained_intron

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002399 IMP MHC class II protein complex assembly
GO:0002503 IDA peptide antigen assembly with MHC class II protein complex
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042613 IDA:IEA MHC class II protein complex
GO:2001190 IMP positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Homologs

No Homologs available.

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