C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class I, C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000228299 HLA-C 9606 - CHR_HSCHR6_MHC_DBB_CTG1:31260956-31264327 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000420206 HLA-C-001 31260956-31264327 protein_coding
  ENST00000422921 HLA-C-004 31260956-31264283 protein_coding
  ENST00000454033 HLA-C-007 31262415-31264266 protein_coding
  ENST00000456487 HLA-C-002 31260956-31264290 protein_coding
  ENST00000458192 HLA-C-003 31260956-31264283 protein_coding
  ENST00000468663 HLA-C-011 31260956-31261871 retained_intron
  ENST00000474724 HLA-C-010 31260956-31262623 retained_intron
  ENST00000479595 HLA-C-006 31260956-31264302 nonsense_mediated_decay
  ENST00000482179 HLA-C-012 31263300-31264287 retained_intron
  ENST00000494823 HLA-C-008 31262422-31264327 retained_intron
  ENST00000495635 HLA-C-005 31260956-31264247 retained_intron
  ENST00000495725 HLA-C-009 31262411-31264270 processed_transcript

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0005515 IEA protein binding
GO:0005783 ISS:IDA endoplasmic reticulum
GO:0005794 ISS:IDA Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 NAS:IEA immune response
GO:0009986 ISS cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0031901 TAS early endosome membrane
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 ISS peptide antigen binding
GO:0042612 ISS:IEA MHC class I protein complex
GO:0046977 IDA TAP binding
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

No Homologs available.

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