C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class I, E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000229252 HLA-E 9606 + CHR_HSCHR6_MHC_DBB_CTG1:30479645-30484444 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000415289 HLA-E-001 30479706-30484444 protein_coding
  ENST00000462399 HLA-E-003 30479751-30481522 retained_intron
  ENST00000486452 HLA-E-002 30479749-30480604 retained_intron
  ENST00000621113 HLA-E-204 30479645-30484443 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002476 IDA antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002717 IDA positive regulation of natural killer cell mediated immunity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 IDA cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0031901 TAS early endosome membrane
GO:0042270 IDA protection from natural killer cell mediated cytotoxicity
GO:0042288 IDA MHC class I protein binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 IDA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0045087 TAS innate immune response
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

No Homologs available.

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